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The acquisition of clinically relevant amoxicillin resistance in Streptococcus pneumoniae requires ordered horizontal gene transfer of four loci
Understanding how antimicrobial resistance spreads is critical for optimal application of new treatments. In the naturally competent human pathogen Streptococcus pneumoniae, resistance to β-lactam antibiotics is mediated by recombination events in genes encoding the target proteins, resulting in red...
Autores principales: | Gibson, Paddy S., Bexkens, Evan, Zuber, Sylvia, Cowley, Lauren A., Veening, Jan-Willem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352194/ https://www.ncbi.nlm.nih.gov/pubmed/35877768 http://dx.doi.org/10.1371/journal.ppat.1010727 |
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