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Computational Tools to Expedite the Identification of Potential PXR Modulators in Complex Natural Product Mixtures: A Case Study with Five Closely Related Licorice Species

[Image: see text] The genus Glycyrrhiza, comprising approximately 36 spp., possesses complex structural diversity and is documented to possess a wide spectrum of biological activities. Understanding and finding the mechanisms of efficacy or safety for a plant-based therapy is very challenging, yet i...

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Detalles Bibliográficos
Autores principales: Alhusban, Manal, Pandey, Pankaj, Ahn, Jongmin, Avula, Bharathi, Haider, Saqlain, Avonto, Cristina, Ali, Zulfiqar, Khan, Shabana I., Ferreira, Daneel, Khan, Ikhlas A., Chittiboyina, Amar G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352242/
https://www.ncbi.nlm.nih.gov/pubmed/35936409
http://dx.doi.org/10.1021/acsomega.2c03240