Cargando…
Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum
Solitary fibrous tumours of the pleura are a rare finding; those with brain metastases are rarer still. Here, we present the evolution of a pleural solitary fibrous tumour in a 70-year-old male treated surgically, and subsequent brain metastasis requiring emergent craniotomy and excision. The patien...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352268/ https://www.ncbi.nlm.nih.gov/pubmed/35935465 http://dx.doi.org/10.1093/jscr/rjac344 |
_version_ | 1784762619288092672 |
---|---|
author | Williams, Catherine French, Daniel Christie, Sean Castonguay, Mathieu Wallace, Alison |
author_facet | Williams, Catherine French, Daniel Christie, Sean Castonguay, Mathieu Wallace, Alison |
author_sort | Williams, Catherine |
collection | PubMed |
description | Solitary fibrous tumours of the pleura are a rare finding; those with brain metastases are rarer still. Here, we present the evolution of a pleural solitary fibrous tumour in a 70-year-old male treated surgically, and subsequent brain metastasis requiring emergent craniotomy and excision. The patient received adjuvant radiotherapy to the brain and had no recurrence of brain metastases; however, 1 year surveillance imaging demonstrated metastases to the lungs, liver and spleen for which he received chemotherapy but eventually succumbed to the disease process. Solitary fibrous tumours are most often slow-growing, relatively benign neoplasms. However, up to 10% are malignant. This case highlights the importance of surgical resection of these benign tumours with malignant potential. |
format | Online Article Text |
id | pubmed-9352268 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-93522682022-08-05 Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum Williams, Catherine French, Daniel Christie, Sean Castonguay, Mathieu Wallace, Alison J Surg Case Rep Case Report Solitary fibrous tumours of the pleura are a rare finding; those with brain metastases are rarer still. Here, we present the evolution of a pleural solitary fibrous tumour in a 70-year-old male treated surgically, and subsequent brain metastasis requiring emergent craniotomy and excision. The patient received adjuvant radiotherapy to the brain and had no recurrence of brain metastases; however, 1 year surveillance imaging demonstrated metastases to the lungs, liver and spleen for which he received chemotherapy but eventually succumbed to the disease process. Solitary fibrous tumours are most often slow-growing, relatively benign neoplasms. However, up to 10% are malignant. This case highlights the importance of surgical resection of these benign tumours with malignant potential. Oxford University Press 2022-08-04 /pmc/articles/PMC9352268/ /pubmed/35935465 http://dx.doi.org/10.1093/jscr/rjac344 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Williams, Catherine French, Daniel Christie, Sean Castonguay, Mathieu Wallace, Alison Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum |
title | Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum |
title_full | Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum |
title_fullStr | Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum |
title_full_unstemmed | Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum |
title_short | Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum |
title_sort | pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352268/ https://www.ncbi.nlm.nih.gov/pubmed/35935465 http://dx.doi.org/10.1093/jscr/rjac344 |
work_keys_str_mv | AT williamscatherine pleuralsolitaryfibroustumourwithbrainmetastasisanaggressivetumourandpathologicconundrum AT frenchdaniel pleuralsolitaryfibroustumourwithbrainmetastasisanaggressivetumourandpathologicconundrum AT christiesean pleuralsolitaryfibroustumourwithbrainmetastasisanaggressivetumourandpathologicconundrum AT castonguaymathieu pleuralsolitaryfibroustumourwithbrainmetastasisanaggressivetumourandpathologicconundrum AT wallacealison pleuralsolitaryfibroustumourwithbrainmetastasisanaggressivetumourandpathologicconundrum |