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Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum

Solitary fibrous tumours of the pleura are a rare finding; those with brain metastases are rarer still. Here, we present the evolution of a pleural solitary fibrous tumour in a 70-year-old male treated surgically, and subsequent brain metastasis requiring emergent craniotomy and excision. The patien...

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Autores principales: Williams, Catherine, French, Daniel, Christie, Sean, Castonguay, Mathieu, Wallace, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352268/
https://www.ncbi.nlm.nih.gov/pubmed/35935465
http://dx.doi.org/10.1093/jscr/rjac344
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author Williams, Catherine
French, Daniel
Christie, Sean
Castonguay, Mathieu
Wallace, Alison
author_facet Williams, Catherine
French, Daniel
Christie, Sean
Castonguay, Mathieu
Wallace, Alison
author_sort Williams, Catherine
collection PubMed
description Solitary fibrous tumours of the pleura are a rare finding; those with brain metastases are rarer still. Here, we present the evolution of a pleural solitary fibrous tumour in a 70-year-old male treated surgically, and subsequent brain metastasis requiring emergent craniotomy and excision. The patient received adjuvant radiotherapy to the brain and had no recurrence of brain metastases; however, 1 year surveillance imaging demonstrated metastases to the lungs, liver and spleen for which he received chemotherapy but eventually succumbed to the disease process. Solitary fibrous tumours are most often slow-growing, relatively benign neoplasms. However, up to 10% are malignant. This case highlights the importance of surgical resection of these benign tumours with malignant potential.
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spelling pubmed-93522682022-08-05 Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum Williams, Catherine French, Daniel Christie, Sean Castonguay, Mathieu Wallace, Alison J Surg Case Rep Case Report Solitary fibrous tumours of the pleura are a rare finding; those with brain metastases are rarer still. Here, we present the evolution of a pleural solitary fibrous tumour in a 70-year-old male treated surgically, and subsequent brain metastasis requiring emergent craniotomy and excision. The patient received adjuvant radiotherapy to the brain and had no recurrence of brain metastases; however, 1 year surveillance imaging demonstrated metastases to the lungs, liver and spleen for which he received chemotherapy but eventually succumbed to the disease process. Solitary fibrous tumours are most often slow-growing, relatively benign neoplasms. However, up to 10% are malignant. This case highlights the importance of surgical resection of these benign tumours with malignant potential. Oxford University Press 2022-08-04 /pmc/articles/PMC9352268/ /pubmed/35935465 http://dx.doi.org/10.1093/jscr/rjac344 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Williams, Catherine
French, Daniel
Christie, Sean
Castonguay, Mathieu
Wallace, Alison
Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum
title Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum
title_full Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum
title_fullStr Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum
title_full_unstemmed Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum
title_short Pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum
title_sort pleural solitary fibrous tumour with brain metastasis: an aggressive tumour and pathologic conundrum
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352268/
https://www.ncbi.nlm.nih.gov/pubmed/35935465
http://dx.doi.org/10.1093/jscr/rjac344
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