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Curcumin partly prevents ISG15 activation via ubiquitin-activating enzyme E1-like protein and decreases ISGylation

The expression of the ubiquitin-like molecule interferon-stimulated gene 15 kDa (ISG15) and post-translational protein modification by ISG15 (ISGylation) are strongly activated by interferons or pathogen infection, suggesting that ISG15 and ISGylation play an important role in innate immune response...

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Detalles Bibliográficos
Autores principales: Oki, Nodoka, Yamada, Shino, Tanaka, Tamaki, Fukui, Hiromi, Hatakeyama, Shigetsugu, Okumura, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352433/
https://www.ncbi.nlm.nih.gov/pubmed/35952613
http://dx.doi.org/10.1016/j.bbrc.2022.08.003