NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors

“Tumor-educated platelets” have recently generated substantial interest for the diagnosis of cancer. We hypothesized that tumor educated platelets from patients with brain tumors will reflect altered metabolism compared to platelets from healthy volunteers. Here, in a pilot study, we have employed n...

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Detalles Bibliográficos
Autores principales: Pudakalakatti, Shivanand, Audia, Alessandra, Mukhopadhyay, Anirudh, Enriquez, José S., Bourgeois, Dontrey, Tayob, Nabihah, Zacharias, Niki M., Millward, Steven W., Carson, Daniel, Farach-Carson, Mary C., Lang, Frederick F., Heimberger, Amy B., Bhat, Krishna P., Bhattacharya, Pratip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352435/
https://www.ncbi.nlm.nih.gov/pubmed/35937580
http://dx.doi.org/10.3390/reports4040032
Descripción
Sumario:“Tumor-educated platelets” have recently generated substantial interest for the diagnosis of cancer. We hypothesized that tumor educated platelets from patients with brain tumors will reflect altered metabolism compared to platelets from healthy volunteers. Here, in a pilot study, we have employed nuclear magnetic resonance (NMR) spectroscopy in platelets from brain tumor patients to demonstrate altered metabolism compared to the platelets obtained from healthy volunteers.

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