NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors

“Tumor-educated platelets” have recently generated substantial interest for the diagnosis of cancer. We hypothesized that tumor educated platelets from patients with brain tumors will reflect altered metabolism compared to platelets from healthy volunteers. Here, in a pilot study, we have employed n...

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Autores principales: Pudakalakatti, Shivanand, Audia, Alessandra, Mukhopadhyay, Anirudh, Enriquez, José S., Bourgeois, Dontrey, Tayob, Nabihah, Zacharias, Niki M., Millward, Steven W., Carson, Daniel, Farach-Carson, Mary C., Lang, Frederick F., Heimberger, Amy B., Bhat, Krishna P., Bhattacharya, Pratip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352435/
https://www.ncbi.nlm.nih.gov/pubmed/35937580
http://dx.doi.org/10.3390/reports4040032
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author Pudakalakatti, Shivanand
Audia, Alessandra
Mukhopadhyay, Anirudh
Enriquez, José S.
Bourgeois, Dontrey
Tayob, Nabihah
Zacharias, Niki M.
Millward, Steven W.
Carson, Daniel
Farach-Carson, Mary C.
Lang, Frederick F.
Heimberger, Amy B.
Bhat, Krishna P.
Bhattacharya, Pratip K.
author_facet Pudakalakatti, Shivanand
Audia, Alessandra
Mukhopadhyay, Anirudh
Enriquez, José S.
Bourgeois, Dontrey
Tayob, Nabihah
Zacharias, Niki M.
Millward, Steven W.
Carson, Daniel
Farach-Carson, Mary C.
Lang, Frederick F.
Heimberger, Amy B.
Bhat, Krishna P.
Bhattacharya, Pratip K.
author_sort Pudakalakatti, Shivanand
collection PubMed
description “Tumor-educated platelets” have recently generated substantial interest for the diagnosis of cancer. We hypothesized that tumor educated platelets from patients with brain tumors will reflect altered metabolism compared to platelets from healthy volunteers. Here, in a pilot study, we have employed nuclear magnetic resonance (NMR) spectroscopy in platelets from brain tumor patients to demonstrate altered metabolism compared to the platelets obtained from healthy volunteers.
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spelling pubmed-93524352022-08-04 NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors Pudakalakatti, Shivanand Audia, Alessandra Mukhopadhyay, Anirudh Enriquez, José S. Bourgeois, Dontrey Tayob, Nabihah Zacharias, Niki M. Millward, Steven W. Carson, Daniel Farach-Carson, Mary C. Lang, Frederick F. Heimberger, Amy B. Bhat, Krishna P. Bhattacharya, Pratip K. Reports (MDPI) Article “Tumor-educated platelets” have recently generated substantial interest for the diagnosis of cancer. We hypothesized that tumor educated platelets from patients with brain tumors will reflect altered metabolism compared to platelets from healthy volunteers. Here, in a pilot study, we have employed nuclear magnetic resonance (NMR) spectroscopy in platelets from brain tumor patients to demonstrate altered metabolism compared to the platelets obtained from healthy volunteers. 2021-12 2021-10-01 /pmc/articles/PMC9352435/ /pubmed/35937580 http://dx.doi.org/10.3390/reports4040032 Text en https://creativecommons.org/licenses/by/4.0/This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pudakalakatti, Shivanand
Audia, Alessandra
Mukhopadhyay, Anirudh
Enriquez, José S.
Bourgeois, Dontrey
Tayob, Nabihah
Zacharias, Niki M.
Millward, Steven W.
Carson, Daniel
Farach-Carson, Mary C.
Lang, Frederick F.
Heimberger, Amy B.
Bhat, Krishna P.
Bhattacharya, Pratip K.
NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors
title NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors
title_full NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors
title_fullStr NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors
title_full_unstemmed NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors
title_short NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors
title_sort nmr spectroscopy-based metabolomics of platelets to analyze brain tumors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352435/
https://www.ncbi.nlm.nih.gov/pubmed/35937580
http://dx.doi.org/10.3390/reports4040032
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