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Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the angiotensin-converting enzyme 2 (ACE2) receptor, a critical component of the kallikrein-kinin system. Its dysregulation may lead to increased vascular permeability and release of inflammatory chemokines. Interactio...

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Detalles Bibliográficos
Autores principales: Martens, Caroline P., Van Mol, Pierre, Wauters, Joost, Wauters, Els, Gangnus, Tanja, Noppen, Bernard, Callewaert, Hanne, Feyen, Jean H.M., Liesenborghs, Laurens, Heylen, Elisabeth, Jansen, Sander, Pereira, Leydi Carolina Velásquez, Kraisin, Sirima, Guler, Ipek, Engelen, Matthias M., Ockerman, Anna, Van Herck, Anke, Vos, Robin, Vandenbriele, Christophe, Meersseman, Philippe, Hermans, Greet, Wilmer, Alexander, Martinod, Kimberly, Burckhardt, Bjoern B., Vanhove, Marc, Jacquemin, Marc, Verhamme, Peter, Neyts, Johan, Vanassche, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352453/
https://www.ncbi.nlm.nih.gov/pubmed/35939907
http://dx.doi.org/10.1016/j.ebiom.2022.104195