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Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury

BACKGROUND: Intestinal barrier dysfunction is crucial in alcohol-associated liver disease (ALD). The decreased beta-Klotho (KLB) expression caused by gene variation is associated with hyperpermeability in patients with irritable bowel syndrome. Here we investigated the roles of intestinal KLB in mai...

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Detalles Bibliográficos
Autores principales:	Hou, Zhengping, Ding, Qiuying, Li, Yuqi, Zhao, Zhibo, Yan, Fang, Li, Yanping, Wang, Xingxing, Xu, Jingyuan, Chen, Weiting, Wu, Guicheng, Ruan, Xiongzhong, Zhao, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352463/ https://www.ncbi.nlm.nih.gov/pubmed/35908416 http://dx.doi.org/10.1016/j.ebiom.2022.104181

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