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Calcium and the Ca-ATPase SPCA1 modulate plasma membrane abundance of ZIP8 and ZIP14 to regulate Mn(II) uptake in brain microvascular endothelial cells

Manganese (II) accumulation in human brain microvascular endothelial cells is mediated by the metal-ion transporters ZRT IRT-like protein 8 (ZIP8) and ZRT IRT-like protein 14 (ZIP14). The plasma membrane occupancy of ZIP14, in particular, is increased in cells treated with Mn(2+), lipopolysaccharide...

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Detalles Bibliográficos
Autores principales:	Steimle, Brittany L., Bailey, Danielle K., Smith, Frances M., Rosenblum, Shaina L., Kosman, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352541/ https://www.ncbi.nlm.nih.gov/pubmed/35787370 http://dx.doi.org/10.1016/j.jbc.2022.102211

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