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A randomized phase III study of pretransplant conditioning for AML/MDS with fludarabine and once daily IV busulfan ± clofarabine in allogeneic stem cell transplantation

Pretransplant conditioning with Fludarabine (Flu)-Busulfan (Bu) is safe, but clofarabine (Clo) has improved antileukemic activity. Hypothesis: Flu+Clo-Bu (FCB) yields superior progression-free survival (PFS) after allogeneic transplantation. We randomized 250 AML/MDS patients aged 3–70, Karnofsky Sc...

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Detalles Bibliográficos
Autores principales:	Andersson, Borje S., Thall, Peter F., Ma, Junsheng, Valdez, Benigno C., Bassett, Roland, Chen, Julianne, Ahmed, Sairah, Alousi, Amin, Bashir, Qaiser, Ciurea, Stefan, Gulbis, Alison, Cool, Rita, Kawedia, Jitesh, Hosing, Chitra, Kebriaei, Partow, Kornblau, Steve, Myers, Alan, Oran, Betul, Rezvani, Katayoun, Shah, Nina, Shpall, Elizabeth, Parmar, Simrit, Popat, Uday R., Nieto, Yago, Champlin, Richard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352570/ https://www.ncbi.nlm.nih.gov/pubmed/35610308 http://dx.doi.org/10.1038/s41409-022-01705-7

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