Transcriptome and proteome analysis of innate immune responses to inactivated Leptospira and bivalent Leptospira vaccines in canine 030-D cells

Mandatory potency testing of Leptospira vaccine batches relies partially on in vivo procedures, requiring large numbers of laboratory animals. Cell-based assays could replace in vivo tests for vaccine quality control if biomarkers indicative of Leptospira vaccine potency are identified. We investiga...

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Detalles Bibliográficos
Autores principales: Novak, Andreja, Pennings, Jeroen L. A., van der Maas, Larissa, Meiring, Hugo D., Ludwig, Irene, Verkoeijen, Saertje, Rutten, Victor, Broere, Femke, Sloots, Arjen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352656/
https://www.ncbi.nlm.nih.gov/pubmed/35927283
http://dx.doi.org/10.1038/s41598-022-16457-z

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