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Glycan shield of the ebolavirus envelope glycoprotein GP

The envelope glycoprotein GP of the ebolaviruses is essential for host cell entry and the primary target of the host antibody response. GP is heavily glycosylated with up to 17 N-linked sites, numerous O-linked glycans in its disordered mucin-like domain (MLD), and three predicted C-linked mannosyla...

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Detalles Bibliográficos
Autores principales: Peng, Weiwei, Rayaprolu, Vamseedhar, Parvate, Amar D., Pronker, Matti F., Hui, Sean, Parekh, Diptiben, Shaffer, Kelly, Yu, Xiaoying, Saphire, Erica O., Snijder, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352669/
https://www.ncbi.nlm.nih.gov/pubmed/35927436
http://dx.doi.org/10.1038/s42003-022-03767-1