Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies

While vaccination against HIV-1 has been so far unsuccessful, recently broadly neutralizing antibodies (bNAbs) against HIV-1 envelope glycoprotein were shown to induce long-term suppression in the absence of antiretroviral therapy in patients with antibody-sensitive viral reservoirs. The requirement...

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Detalles Bibliográficos
Autores principales: Stam, Jord C., de Maat, Steven, de Jong, Dorien, Arens, Mathia, van Lint, Fenna, Gharu, Lavina, van Roosmalen, Mark H., Roovers, Rob C., Strokappe, Nika M., Wagner, Ralf, Kliche, Alexander, de Haard, Hans J., van Bergen en Henegouwen, Paul M., Nijhuis, Monique, Verrips, C. Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352707/
https://www.ncbi.nlm.nih.gov/pubmed/35927444
http://dx.doi.org/10.1038/s41598-022-15993-y

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