Cargando…

Gastruloids as in vitro models of embryonic blood development with spatial and temporal resolution

Gastruloids are three-dimensional embryonic organoids that reproduce key features of early mammalian development in vitro with unique scalability, accessibility, and spatiotemporal similarity to real embryos. Recently, we adapted the gastruloid culture conditions to promote cardiovascular developmen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rossi, Giuliana, Giger, Sonja, Hübscher, Tania, Lutolf, Matthias P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352713/ https://www.ncbi.nlm.nih.gov/pubmed/35927563 http://dx.doi.org/10.1038/s41598-022-17265-1

Ejemplares similares

Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids
por: Turner, David A., et al.
Publicado: (2017)

Multimodal characterization of murine gastruloid development
por: Suppinger, Simon, et al.
Publicado: (2023)

A New Approach to Generate Gastruloids to Develop Anterior Neural Tissues
por: Girgin, Mehmet, et al.
Publicado: (2023)

Gastruloids generated without exogenous Wnt activation develop anterior neural tissues
por: Girgin, Mehmet U., et al.
Publicado: (2021)

A gastruloid model of the interaction between embryonic and extra-embryonic cell types
por: Bérenger-Currias, Noémie MLP, et al.
Publicado: (2022)

Bioengineering in vitro models of embryonic development
por: Gupta, Ananya, et al.
Publicado: (2021)

Gastruloid Development Competence Discriminates Different States of Pluripotency
por: Cermola, Federica, et al.
Publicado: (2021)

Cardiac Organoids and Gastruloids to Study Physio-Pathological Heart Development
por: Jaconi, Marisa E., et al.
Publicado: (2021)

A combined human gastruloid model of cardiogenesis and neurogenesis
por: Olmsted, Zachary T., et al.
Publicado: (2022)

High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures
por: Minn, Kyaw Thu, et al.
Publicado: (2020)

In vitro teratogenicity testing using a 3D, embryo-like gastruloid system
por: Mantziou, Veronika, et al.
Publicado: (2021)

Gene expression dynamics underlying cell fate emergence in 2D micropatterned human embryonic stem cell gastruloids
por: Minn, Kyaw Thu, et al.
Publicado: (2021)

Generation of human elongating multi-lineage organized cardiac gastruloids
por: Olmsted, Zachary T., et al.
Publicado: (2022)

Recording morphogen signals reveals origins of gastruloid symmetry breaking
por: McNamara, Harold M., et al.
Publicado: (2023)

Budesonide Analogues Preserve Stem Cell Pluripotency and Delay 3D Gastruloid Development
por: Amoroso, Filomena, et al.
Publicado: (2023)

Gastruloid-derived primordial germ cell-like cells develop dynamically within integrated tissues
por: Cooke, Christopher B., et al.
Publicado: (2023)

Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids
por: Olmsted, Zachary T., et al.
Publicado: (2021)

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
por: Yoney, Anna, et al.
Publicado: (2018)

YAP1 regulates the self-organized fate patterning of hESC-derived gastruloids
por: Stronati, Eleonora, et al.
Publicado: (2022)

Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids
por: Hashmi, Ali, et al.
Publicado: (2022)

Microarrayed human bone marrow organoids for modeling blood stem cell dynamics
por: Giger, Sonja, et al.
Publicado: (2022)

Hypoxia induces an early primitive streak signature, enhancing spontaneous elongation and lineage representation in gastruloids
por: López-Anguita, Natalia, et al.
Publicado: (2022)

Stabilization of cell-cell adhesions prevents symmetry breaking and locks in pluripotency in 3D gastruloids
por: Cermola, Federica, et al.
Publicado: (2022)

Nodal is a short-range morphogen with activity that spreads through a relay mechanism in human gastruloids
por: Liu, Lizhong, et al.
Publicado: (2022)

In vitro BioID: mapping the CENP-A microenvironment with high temporal and spatial resolution
por: Remnant, Lucy, et al.
Publicado: (2019)

Tactile Feedback Display with Spatial and Temporal Resolutions
por: Vishniakou, Siarhei, et al.
Publicado: (2013)

TBXT dose sensitivity and the decoupling of nascent mesoderm specification from EMT progression in 2D human gastruloids
por: Bulger, Emily A., et al.
Publicado: (2023)

Single-cell analyses identify bioengineered niches for enhanced maintenance of hematopoietic stem cells
por: Roch, Aline, et al.
Publicado: (2017)

Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids
por: Chhabra, Sapna, et al.
Publicado: (2019)

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects
por: Galgoczi, Szilvia, et al.
Publicado: (2021)

Decoding Rich Spatial Information with High Temporal Resolution
por: Stokes, Mark G., et al.
Publicado: (2015)

ERRATUM: Tactile Feedback Display with Spatial and Temporal Resolutions
por: Vishniakou, Siarhei, et al.
Publicado: (2013)

Predicting future climate at high spatial and temporal resolution
por: Maclean, Ilya M. D.
Publicado: (2019)

Temporal trend evaluation in monitoring programs with high spatial resolution and low temporal resolution using geographically weighted regression models
por: von Brömssen, Claudia, et al.
Publicado: (2023)

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity
por: Vannini, Nicola, et al.
Publicado: (2016)

Understanding embryonic development at single-cell resolution
por: Jiang, Mengmeng, et al.
Publicado: (2021)

Emotional cues enhance the attentional effects on spatial and temporal resolution
por: Bocanegra, Bruno R., et al.
Publicado: (2011)

Spatial and temporal resolution of metabolic dysregulation in the Sugen hypoxia model of pulmonary hypertension
por: Simpson, Catherine E., et al.
Publicado: (2023)

The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development
por: Silva, Jeane, et al.
Publicado: (2011)

High-Temporal-Resolution High-Spatial-Resolution Spaceborne SAR Based on Continuously Varying PRF
por: Men, Zhirong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gnr33teesg7bvkahdanvoo41pn