New use for old drug: Local delivery of puerarin facilitates critical-size defect repair in rats by promoting angiogenesis and osteogenesis

OBJECTIVES: Large bone defect repair is a challenging clinical problem due to limited self-repair ability. A well-designed bone filling product should possess the ability to induce tissue in-growth and facilitate neovascularization and new bone formation. Puerarin has been used in clinics for a long...

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Detalles Bibliográficos
Autores principales: Cao, Huijuan, Li, Lingli, Li, Ling, Meng, Xiangbo, Liu, Yanzhi, Cheng, Wenxiang, Zhang, Peng, Gao, Yongbo, Qin, Ling, Wang, Xinluan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352809/
https://www.ncbi.nlm.nih.gov/pubmed/35979175
http://dx.doi.org/10.1016/j.jot.2022.05.003

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