Improving MGMT methylation status prediction of glioblastoma through optimizing radiomics features using genetic algorithm-based machine learning approach

O6-Methylguanine-DNA-methyltransferase (MGMT) promoter methylation was shown in many studies to be an important predictive biomarker for temozolomide (TMZ) resistance and poor progression-free survival in glioblastoma multiforme (GBM) patients. However, identifying the MGMT methylation status using...

Descripción completa

Detalles Bibliográficos
Autores principales: Do, Duyen Thi, Yang, Ming-Ren, Lam, Luu Ho Thanh, Le, Nguyen Quoc Khanh, Wu, Yu-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352871/
https://www.ncbi.nlm.nih.gov/pubmed/35927323
http://dx.doi.org/10.1038/s41598-022-17707-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352871/
https://www.ncbi.nlm.nih.gov/pubmed/35927323
http://dx.doi.org/10.1038/s41598-022-17707-w

Ejemplares similares