Cargando…

PKCα and PKCδ: Friends and Rivals

PKC comprises a large family of serine/threonine kinases that share a requirement for allosteric activation by lipids. While PKC isoforms have significant homology, functional divergence is evident among subfamilies and between individual PKC isoforms within a subfamily. Here, we highlight these dif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Black, Jennifer D., Affandi, Trisiani, Black, Adrian R., Reyland, Mary E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	JBC Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352922/ https://www.ncbi.nlm.nih.gov/pubmed/35760100 http://dx.doi.org/10.1016/j.jbc.2022.102194

Ejemplares similares

PKCδ regulates chromatin remodeling and DNA repair through SIRT6
por: Affandi, Trisiani, et al.
Publicado: (2023)

PKC regulation of ion channels: The involvement of PIP(2)
por: Gada, Kirin D., et al.
Publicado: (2022)

PKCδ regulates integrin α(V)β(3) expression and transformed growth of K-ras dependent lung cancer cells
por: Symonds, Jennifer M., et al.
Publicado: (2016)

Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
por: Cooke, Mariana, et al.
Publicado: (2023)

Metabolic reprogramming contributes to radioprotection by protein kinase Cδ
por: Ohm, Angela M., et al.
Publicado: (2023)

Overexpressed PKCδ Downregulates the Expression of PKCα in B16F10 Melanoma: Induction of Apoptosis by PKCδ via Ceramide Generation
por: Halder, Kuntal, et al.
Publicado: (2014)

Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets
por: Pears, Catherine J., et al.
Publicado: (2008)

Co-dependency of PKCδ and K-Ras: Inverse association with cytotoxic drug sensitivity in KRAS mutant lung cancer
por: Ohm, Angela M., et al.
Publicado: (2017)

A novel antiproliferative PKCα-Ras-ERK signaling axis in intestinal epithelial cells
por: Kaur, Navneet, et al.
Publicado: (2022)

Src, PKCα, and PKCδ are required for αvβ3 integrin-mediated metastatic melanoma invasion
por: Putnam, Andrew J, et al.
Publicado: (2009)

Role of FGFR2b expression and signaling in keratinocyte differentiation: sequential involvement of PKCδ and PKCα
por: Rosato, Benedetta, et al.
Publicado: (2018)

PKCδ Blues for the β-Cell
por: Schmitz-Peiffer, Carsten, et al.
Publicado: (2010)

PKCδ regulates the vascular biology in diabetic atherosclerosis
por: Qin, Peiliang, et al.
Publicado: (2023)

Tyrosine kinase inhibitors protect the salivary gland from radiation damage by increasing DNA double-strand break repair
por: Affandi, Trisiani, et al.
Publicado: (2021)

PKCα and PKCδ Regulate ADAM17-Mediated Ectodomain Shedding of Heparin Binding-EGF through Separate Pathways
por: Kveiborg, Marie, et al.
Publicado: (2011)

Selective regulation of osteoclast adhesion and spreading by PLCγ/PKCα-PKCδ/RhoA-Rac1 signaling
por: Kim, Jin-Man, et al.
Publicado: (2018)

Atypical histone targets of PHD fingers
por: Black, Joshua C., et al.
Publicado: (2023)

B7-H4 expression is upregulated by PKCδ activation and contributes to PKCδ-induced cell motility in colorectal cancer
por: Zhou, Bin, et al.
Publicado: (2022)

Crosstalk between PKCα and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium
por: Hsu, Alice H., et al.
Publicado: (2018)

PKCδ deficiency inhibits fetal development and is associated with heart elastic fiber hyperplasia and lung inflammation in adult PKCδ knockout mice
por: Niino, Yuko S., et al.
Publicado: (2021)

Essential Role Of High Glucose-Induced Overexpression Of PKCβ And PKCδ In GLP-1 Resistance In Rodent Cardiomyocytes
por: Pan, Xietian, et al.
Publicado: (2019)

Increase in PKCα Activity during Heart Failure Despite the Stimulation of PKCα Braking Mechanism
por: Aslam, Naveed
Publicado: (2020)

Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism
por: Li, Mengyao, et al.
Publicado: (2015)

Control of nuclear-cytoplasmic shuttling of Ankrd54 by PKCδ
por: Samuels, Amy L, et al.
Publicado: (2017)

Role for PKC δ in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells
por: Ruvolo, Vivian R., et al.
Publicado: (2010)

Impaired respiratory burst contributes to infections in PKCδ-deficient patients
por: Neehus, Anna-Lena, et al.
Publicado: (2021)

Combination of PKCδ Inhibition with Conventional TKI Treatment to Target CML Models
por: Muselli, Fabien, et al.
Publicado: (2021)

Two Faces of Protein Kinase Cδ: The Contrasting Roles of PKCδ in Cell Survival and Cell Death
por: Basu, Alakananda, et al.
Publicado: (2010)

PTPL1 and PKCδ contribute to proapoptotic signalling in prostate cancer cells
por: Castilla, C, et al.
Publicado: (2013)

Role and Mechanism of PKC-δ for Cardiovascular Disease: Current Status and Perspective
por: Miao, Li-na, et al.
Publicado: (2022)

Inhibition of PKC‐δ reduce rhabdomyolysis‐induced acute kidney injury
por: Wu, Dengke, et al.
Publicado: (2022)

Duodenal PKC-δ and Cholecystokinin Signaling Axis Regulates Glucose Production
por: Breen, Danna M., et al.
Publicado: (2011)

Identification of lipocalin-2 as a PKCδ phosphorylation substrate in neutrophils
por: Weng, Yi-Chinn, et al.
Publicado: (2015)

The parasites of my rival are my friends
por: Orlansky, Sigal, et al.
Publicado: (2023)

Protein Kinase C (Pkc)-δ Mediates Arginine-Induced Glucagon Secretion in Pancreatic α-Cells
por: Honzawa, Norikiyo, et al.
Publicado: (2022)

Targeting MDMX and PKCδ to improve current uveal melanoma therapeutic strategies
por: Heijkants, R. C., et al.
Publicado: (2018)

Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors
por: Rao, Tata Nageswara, et al.
Publicado: (2018)

Mitochondrial hydrogen peroxide production by pyruvate dehydrogenase and α-ketoglutarate dehydrogenase in oxidative eustress and oxidative distress
por: Chalifoux, Olivia, et al.
Publicado: (2023)

Curtailing side effects in chemotherapy: a tale of PKCδ in cisplatin treatment
por: Pabla, Navjotsingh, et al.
Publicado: (2012)

Central amygdala PKC-δ(+) neurons mediate the influence of multiple anorexigenic signals
por: Cai, Haijiang, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_952s85qds0v5cl13rgeiut1oih