IL-10 Overexpression After BCG Vaccination Does Not Impair Control of Mycobacterium tuberculosis Infection

Control of tuberculosis depends on the rapid expression of protective CD4(+) T-cell responses in the Mycobacterium tuberculosis (Mtb)-infected lungs. We have recently shown that the immunomodulatory cytokine IL-10 acts intrinsically in CD4(+) T cells and impairs their parenchymal migratory capacity,...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferreira, Catarina M., Micheli, Consuelo, Barreira-Silva, Palmira, Barbosa, Ana Margarida, Resende, Mariana, Vilanova, Manuel, Silvestre, Ricardo, Cunha, Cristina, Carvalho, Agostinho, Rodrigues, Fernando, Correia-Neves, Margarida, Castro, António Gil, Torrado, Egídio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353026/
https://www.ncbi.nlm.nih.gov/pubmed/35935958
http://dx.doi.org/10.3389/fimmu.2022.946181

Ejemplares similares

Ejemplares similares