Sildenafil, a Type-5 Phosphodiesterase Inhibitor, Fails to Reverse Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression in Cells Isolated From Tuberculosis Patients

Successful TB treatment is hampered by increasing resistance to the two most effective first-line anti-TB drugs, namely isoniazid and rifampicin, thus innovative therapies focused on host processes, termed host-directed therapies (HDTs), are promising novel approaches for increasing treatment effica...

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Detalles Bibliográficos
Autores principales: Leukes, Vinzeigh N., Malherbe, Stephanus T., Hiemstra, Andriette, Kotze, Leigh A., Roos, Kelly, Keyser, Alana, De Swardt, Dalene, Gutschmidt, Andrea, Walzl, Gerhard, du Plessis, Nelita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353143/
https://www.ncbi.nlm.nih.gov/pubmed/35935981
http://dx.doi.org/10.3389/fimmu.2022.883886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353143/
https://www.ncbi.nlm.nih.gov/pubmed/35935981
http://dx.doi.org/10.3389/fimmu.2022.883886

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