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Sildenafil, a Type-5 Phosphodiesterase Inhibitor, Fails to Reverse Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression in Cells Isolated From Tuberculosis Patients

Successful TB treatment is hampered by increasing resistance to the two most effective first-line anti-TB drugs, namely isoniazid and rifampicin, thus innovative therapies focused on host processes, termed host-directed therapies (HDTs), are promising novel approaches for increasing treatment effica...

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Detalles Bibliográficos
Autores principales:	Leukes, Vinzeigh N., Malherbe, Stephanus T., Hiemstra, Andriette, Kotze, Leigh A., Roos, Kelly, Keyser, Alana, De Swardt, Dalene, Gutschmidt, Andrea, Walzl, Gerhard, du Plessis, Nelita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353143/ https://www.ncbi.nlm.nih.gov/pubmed/35935981 http://dx.doi.org/10.3389/fimmu.2022.883886

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