Mapping Phenotypic Plasticity upon the Cancer Cell State Landscape Using Manifold Learning

ABSTRACT: Phenotypic plasticity describes the ability of cancer cells to undergo dynamic, nongenetic cell state changes that amplify cancer heterogeneity to promote metastasis and therapy evasion. Thus, cancer cells occupy a continuous spectrum of phenotypic states connected by trajectories defining...

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Detalles Bibliográficos
Autores principales: Burkhardt, Daniel B., San Juan, Beatriz P., Lock, John G., Krishnaswamy, Smita, Chaffer, Christine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353259/
https://www.ncbi.nlm.nih.gov/pubmed/35736000
http://dx.doi.org/10.1158/2159-8290.CD-21-0282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353259/
https://www.ncbi.nlm.nih.gov/pubmed/35736000
http://dx.doi.org/10.1158/2159-8290.CD-21-0282

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