Cargando…
Mapping Phenotypic Plasticity upon the Cancer Cell State Landscape Using Manifold Learning
ABSTRACT: Phenotypic plasticity describes the ability of cancer cells to undergo dynamic, nongenetic cell state changes that amplify cancer heterogeneity to promote metastasis and therapy evasion. Thus, cancer cells occupy a continuous spectrum of phenotypic states connected by trajectories defining...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for Cancer Research
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353259/ https://www.ncbi.nlm.nih.gov/pubmed/35736000 http://dx.doi.org/10.1158/2159-8290.CD-21-0282 |