SARS‐CoV‐2 spike protein enhances MAP4K3/GLK‐induced ACE2 stability in COVID‐19

ACE2 on epithelial cells is the SARS‐CoV‐2 entry receptor. Single‐cell RNA‐sequencing data derived from two COVID‐19 cohorts revealed that MAP4K3/GLK‐positive epithelial cells were increased in patients. SARS‐CoV‐2‐induced GLK overexpression in epithelial cells was correlated with COVID‐19 severity...

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Detalles Bibliográficos
Autores principales: Chuang, Huai‐Chia, Hsueh, Chia‐Hsin, Hsu, Pu‐Ming, Huang, Rou‐Huei, Tsai, Ching‐Yi, Chung, Nai‐Hsiang, Chow, Yen‐Hung, Tan, Tse‐Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353388/
https://www.ncbi.nlm.nih.gov/pubmed/35894122
http://dx.doi.org/10.15252/emmm.202215904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353388/
https://www.ncbi.nlm.nih.gov/pubmed/35894122
http://dx.doi.org/10.15252/emmm.202215904

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