Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors

Neoantigen‐directed therapy lacks preclinical models recapitulating neoantigen characteristics of original tumors. It is urgent to develop a platform to assess T cell response for neoantigen screening. Here, immunogenic potential of neoantigen‐peptides of tumor tissues and matched organoids (n = 27...

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Detalles Bibliográficos
Autores principales: Wang, Wenwen, Yuan, Tinggan, Ma, Lili, Zhu, Yanjing, Bao, Jinxia, Zhao, Xiaofang, Zhao, Yan, Zong, Yali, Zhang, Yani, Yang, Shuai, Qiu, Xinyao, Shen, Siyun, Wu, Rui, Wu, Tong, Wang, Hongyang, Gao, Dong, Wang, Peng, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353440/
https://www.ncbi.nlm.nih.gov/pubmed/35665491
http://dx.doi.org/10.1002/advs.202105810

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