Activation of cGAS‐STING by Lethal Malaria N67C Dictates Immunity and Mortality through Induction of CD11b(+)Ly6C(hi) Proinflammatory Monocytes

Cyclic GMP‐AMP synthase (cGAS) and stimulator of interferon genes (STING) play critical roles in the innate immunity against infectious diseases and are required to link pathogen DNA sensing to immune responses. However, the mechanisms by which cGAS‐STING‐induced cytokines suppress the adaptive immu...

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Detalles Bibliográficos
Autores principales: Du, Yang, Luo, Yien, Hu, Zhiqiang, Lu, Jiansen, Liu, Xin, Xing, Changsheng, Wu, Jian, Duan, Tianhao, Chu, Junjun, Wang, Helen Y., Su, Xin‐zhuan, Yu, Xiao, Wang, Rong‐Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353503/
https://www.ncbi.nlm.nih.gov/pubmed/35635376
http://dx.doi.org/10.1002/advs.202103701

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