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Endoplasmic Reticulum Stress and Dysregulated Autophagy in Human Pancreatic Beta Cells

Pancreatic beta cell homeostasis is crucial for the synthesis and secretion of insulin; disruption of homeostasis causes diabetes, and is a treatment target. Adaptation to endoplasmic reticulum (ER) stress through the unfolded protein response (UPR) and adequate regulation of autophagy, which are cl...

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Detalles Bibliográficos
Autores principales: Moon, Seoil, Jung, Hye Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353561/
https://www.ncbi.nlm.nih.gov/pubmed/35929171
http://dx.doi.org/10.4093/dmj.2022.0070