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Endoplasmic Reticulum Stress and Dysregulated Autophagy in Human Pancreatic Beta Cells
Pancreatic beta cell homeostasis is crucial for the synthesis and secretion of insulin; disruption of homeostasis causes diabetes, and is a treatment target. Adaptation to endoplasmic reticulum (ER) stress through the unfolded protein response (UPR) and adequate regulation of autophagy, which are cl...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353561/ https://www.ncbi.nlm.nih.gov/pubmed/35929171 http://dx.doi.org/10.4093/dmj.2022.0070 |