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A combination of stromal PD‐L1 and tumoral nuclear β‐catenin expression as an indicator of colorectal carcinoma progression and resistance to chemoradiotherapy in locally advanced rectal carcinoma
Programmed cell death‐1 (PD‐1) and its ligand (PD‐L1) are significant mediators of immune suppression in the tumor microenvironment. We focused on the immunological impact of PD‐1/PD‐L1 signaling during tumor progression in colorectal carcinoma (CRC) and its association with resistance to neoadjuvan...
Autores principales: | Takahashi, Hiroyuki, Watanabe, Hirono, Hashimura, Miki, Matsumoto, Toshihide, Yokoi, Ako, Nakagawa, Mayu, Ishibashi, Yu, Ito, Takashi, Ohhigata, Kensuke, Saegusa, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353658/ https://www.ncbi.nlm.nih.gov/pubmed/35762092 http://dx.doi.org/10.1002/cjp2.285 |
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