PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition

The two most common antibody targeting principles in oncology are the induction of direct antitumor effects and the release of antitumor T cell immunity by immune checkpoint blockade. These two principles, however, may be overlapping if the targeted checkpoint molecule is not located on the immune c...

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Detalles Bibliográficos
Autores principales: Claaß, Luise Victoria, Schultheiß, Christoph, Scholz, Rebekka, Paschold, Lisa, Simnica, Donjete, Heinemann, Volker, Stintzing, Sebastian, Binder, Mascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353709/
https://www.ncbi.nlm.nih.gov/pubmed/35936668
http://dx.doi.org/10.3389/fonc.2022.941666

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