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Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit

BACKGROUND: Postoperative delirium is common in patients who undergo neurosurgery for craniocerebral injury. However, there is no specific medical test to predict postoperative delirium to date. AIM: To explore risk factors for postoperative delirium in patients with craniocerebral injury in the neu...

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Autores principales: Chen, Ri-Yu, Zhong, Chang-Hui, Chen, Wei, Lin, Ming, Feng, Chang-Fu, Chen, Chang-Neng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353923/
https://www.ncbi.nlm.nih.gov/pubmed/36158014
http://dx.doi.org/10.12998/wjcc.v10.i21.7341
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author Chen, Ri-Yu
Zhong, Chang-Hui
Chen, Wei
Lin, Ming
Feng, Chang-Fu
Chen, Chang-Neng
author_facet Chen, Ri-Yu
Zhong, Chang-Hui
Chen, Wei
Lin, Ming
Feng, Chang-Fu
Chen, Chang-Neng
author_sort Chen, Ri-Yu
collection PubMed
description BACKGROUND: Postoperative delirium is common in patients who undergo neurosurgery for craniocerebral injury. However, there is no specific medical test to predict postoperative delirium to date. AIM: To explore risk factors for postoperative delirium in patients with craniocerebral injury in the neurosurgery intensive care unit (ICU). METHODS: A retrospective analysis was performed in 120 patients with craniocerebral injury admitted to Hainan People’s Hospital/Hainan Hospital Affiliated to Hainan Medical University, The First Affiliated Hospital of Hainan Medical University, and The Second Affiliated Hospital of Hainan Medical University between January 2018 and January 2020. The patients were categorized into groups based on whether delirium occurred. Of them, 25 patients with delirium were included in the delirium group, and 95 patients without delirium were included in the observation group. Logistic regression analysis was used to explore the association between sex, age, educational level, Glasgow coma scale (GCS), complications (with or without concussion, cerebral contusion, hypoxemia and ventricular compression) and site of injury and delirium. RESULTS: The GCS score above 8 and concomitant disease of cerebral concussion, cerebral contusion, hypoxemia and ventricular compression, and damage to the frontal lobe were associated with delirium in patients admitted to neurosurgical intensive care unit (ICU) (all P < 0.05). However, age, sex, administration more than three medicines, and educational level were not significantly associated with the onset of delirium in patients with craniocerebral injury in the neurosurgical ICU (P < 0.05). Multivariate logistic regression analysis showed that GCS score above 8, cerebral concussion, cerebral contusion, hypoxemia, ventricle compression, and frontal lobe disorders were independent risk factors for delirium in patients with craniocerebral injury in the neurosurgical ICU (P < 0.05). CONCLUSION: GCS score, concussive concussion, cerebral contusion, hypoxemia, ventricle compression, and damage to frontal lobe are risk factors of postoperative delirium.
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spelling pubmed-93539232022-09-23 Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit Chen, Ri-Yu Zhong, Chang-Hui Chen, Wei Lin, Ming Feng, Chang-Fu Chen, Chang-Neng World J Clin Cases Retrospective Study BACKGROUND: Postoperative delirium is common in patients who undergo neurosurgery for craniocerebral injury. However, there is no specific medical test to predict postoperative delirium to date. AIM: To explore risk factors for postoperative delirium in patients with craniocerebral injury in the neurosurgery intensive care unit (ICU). METHODS: A retrospective analysis was performed in 120 patients with craniocerebral injury admitted to Hainan People’s Hospital/Hainan Hospital Affiliated to Hainan Medical University, The First Affiliated Hospital of Hainan Medical University, and The Second Affiliated Hospital of Hainan Medical University between January 2018 and January 2020. The patients were categorized into groups based on whether delirium occurred. Of them, 25 patients with delirium were included in the delirium group, and 95 patients without delirium were included in the observation group. Logistic regression analysis was used to explore the association between sex, age, educational level, Glasgow coma scale (GCS), complications (with or without concussion, cerebral contusion, hypoxemia and ventricular compression) and site of injury and delirium. RESULTS: The GCS score above 8 and concomitant disease of cerebral concussion, cerebral contusion, hypoxemia and ventricular compression, and damage to the frontal lobe were associated with delirium in patients admitted to neurosurgical intensive care unit (ICU) (all P < 0.05). However, age, sex, administration more than three medicines, and educational level were not significantly associated with the onset of delirium in patients with craniocerebral injury in the neurosurgical ICU (P < 0.05). Multivariate logistic regression analysis showed that GCS score above 8, cerebral concussion, cerebral contusion, hypoxemia, ventricle compression, and frontal lobe disorders were independent risk factors for delirium in patients with craniocerebral injury in the neurosurgical ICU (P < 0.05). CONCLUSION: GCS score, concussive concussion, cerebral contusion, hypoxemia, ventricle compression, and damage to frontal lobe are risk factors of postoperative delirium. Baishideng Publishing Group Inc 2022-07-26 2022-07-26 /pmc/articles/PMC9353923/ /pubmed/36158014 http://dx.doi.org/10.12998/wjcc.v10.i21.7341 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Retrospective Study
Chen, Ri-Yu
Zhong, Chang-Hui
Chen, Wei
Lin, Ming
Feng, Chang-Fu
Chen, Chang-Neng
Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit
title Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit
title_full Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit
title_fullStr Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit
title_full_unstemmed Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit
title_short Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit
title_sort risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit
topic Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353923/
https://www.ncbi.nlm.nih.gov/pubmed/36158014
http://dx.doi.org/10.12998/wjcc.v10.i21.7341
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