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Association Between Visceral Adiposity Index and Insulin Resistance: A Cross-Sectional Study Based on US Adults

BACKGROUND: Visceral obesity index (VAI) is an empirical mathematical model used to evaluate the distribution and function of fat. Some studies have shown that VAI may be associated with the development of insulin resistance. In view of the differences in insulin resistance among different ethnic gr...

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Autores principales: Jiang, Kai, Luan, Hong, Pu, Xiaolu, Wang, Mingxiang, Yin, Jiahui, Gong, Rongpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353944/
https://www.ncbi.nlm.nih.gov/pubmed/35937809
http://dx.doi.org/10.3389/fendo.2022.921067
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author Jiang, Kai
Luan, Hong
Pu, Xiaolu
Wang, Mingxiang
Yin, Jiahui
Gong, Rongpeng
author_facet Jiang, Kai
Luan, Hong
Pu, Xiaolu
Wang, Mingxiang
Yin, Jiahui
Gong, Rongpeng
author_sort Jiang, Kai
collection PubMed
description BACKGROUND: Visceral obesity index (VAI) is an empirical mathematical model used to evaluate the distribution and function of fat. Some studies have shown that VAI may be associated with the development of insulin resistance. In view of the differences in insulin resistance among different ethnic groups, this study attempts to analyze the special relationship between VAI and insulin resistance in American adults. METHODS: We conducted a cross-sectional study through NHANES database. A total of 27309 patients over the age of 18 from the United States took part in the survey. It was divided into two groups: the IR-positive group and the IR-negative group. The association of VAI with IR was evaluated by logistic regression analyses mainly, including univariate analysis, multivariate regression analysis, curve fitting analysis and subgroup analysis. RESULTS: The results showed that in the full-adjusted model, there is a strong positive association between VAI level and insulin resistance (OR: 1.28 (1.2~1.37), P<0.001) and there is a threshold effect. CONCLUSIONS: This study suggests that higher VAI levels are associated with insulin resistance. VAI index may be used as a predictor of insulin resistance.
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spelling pubmed-93539442022-08-06 Association Between Visceral Adiposity Index and Insulin Resistance: A Cross-Sectional Study Based on US Adults Jiang, Kai Luan, Hong Pu, Xiaolu Wang, Mingxiang Yin, Jiahui Gong, Rongpeng Front Endocrinol (Lausanne) Endocrinology BACKGROUND: Visceral obesity index (VAI) is an empirical mathematical model used to evaluate the distribution and function of fat. Some studies have shown that VAI may be associated with the development of insulin resistance. In view of the differences in insulin resistance among different ethnic groups, this study attempts to analyze the special relationship between VAI and insulin resistance in American adults. METHODS: We conducted a cross-sectional study through NHANES database. A total of 27309 patients over the age of 18 from the United States took part in the survey. It was divided into two groups: the IR-positive group and the IR-negative group. The association of VAI with IR was evaluated by logistic regression analyses mainly, including univariate analysis, multivariate regression analysis, curve fitting analysis and subgroup analysis. RESULTS: The results showed that in the full-adjusted model, there is a strong positive association between VAI level and insulin resistance (OR: 1.28 (1.2~1.37), P<0.001) and there is a threshold effect. CONCLUSIONS: This study suggests that higher VAI levels are associated with insulin resistance. VAI index may be used as a predictor of insulin resistance. Frontiers Media S.A. 2022-07-22 /pmc/articles/PMC9353944/ /pubmed/35937809 http://dx.doi.org/10.3389/fendo.2022.921067 Text en Copyright © 2022 Jiang, Luan, Pu, Wang, Yin and Gong https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Jiang, Kai
Luan, Hong
Pu, Xiaolu
Wang, Mingxiang
Yin, Jiahui
Gong, Rongpeng
Association Between Visceral Adiposity Index and Insulin Resistance: A Cross-Sectional Study Based on US Adults
title Association Between Visceral Adiposity Index and Insulin Resistance: A Cross-Sectional Study Based on US Adults
title_full Association Between Visceral Adiposity Index and Insulin Resistance: A Cross-Sectional Study Based on US Adults
title_fullStr Association Between Visceral Adiposity Index and Insulin Resistance: A Cross-Sectional Study Based on US Adults
title_full_unstemmed Association Between Visceral Adiposity Index and Insulin Resistance: A Cross-Sectional Study Based on US Adults
title_short Association Between Visceral Adiposity Index and Insulin Resistance: A Cross-Sectional Study Based on US Adults
title_sort association between visceral adiposity index and insulin resistance: a cross-sectional study based on us adults
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353944/
https://www.ncbi.nlm.nih.gov/pubmed/35937809
http://dx.doi.org/10.3389/fendo.2022.921067
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