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Combining Metabolic Engineering and Multiplexed Screening Methods for 3-Hydroxypropionic Acid Production in Pichia pastoris

Production of 3-hydroxypropionic acid (3-HP) in Pichia pastoris (syn. Komagataella phaffii) via the malonyl-CoA pathway has been recently demonstrated using glycerol as a carbon source, but the reported metrics were not commercially relevant. The flux through the heterologous pathway from malonyl-Co...

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Detalles Bibliográficos
Autores principales: Fina, Albert, Heux, Stephanie, Albiol, Joan, Ferrer, Pau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354023/
https://www.ncbi.nlm.nih.gov/pubmed/35935509
http://dx.doi.org/10.3389/fbioe.2022.942304