Use of Wet Milling Combined with Temperature Cycling to Minimize Crystal Agglomeration in a Sequential Antisolvent–Cooling Crystallization

[Image: see text] The objective of the research was to improve the process design of a combined antisolvent–cooling crystallization to reduce the degree of agglomeration of a real active pharmaceutical ingredient product, which was manufactured using a crystallization stage employing a methanol/wate...

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Detalles Bibliográficos
Autores principales: Sun, Zhuang, Quon, Justin L., Papageorgiou, Charles D., Benyahia, Brahim, Rielly, Chris D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354031/
https://www.ncbi.nlm.nih.gov/pubmed/35942120
http://dx.doi.org/10.1021/acs.cgd.1c01510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354031/
https://www.ncbi.nlm.nih.gov/pubmed/35942120
http://dx.doi.org/10.1021/acs.cgd.1c01510

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