Novel DNM1L variants impair mitochondrial dynamics through divergent mechanisms

Imbalances in mitochondrial and peroxisomal dynamics are associated with a spectrum of human neurological disorders. Mitochondrial and peroxisomal fission both involve dynamin-related protein 1 (DRP1) oligomerisation and membrane constriction, although the precise biophysical mechanisms by which dis...

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Detalles Bibliográficos
Autores principales: Nolden, Kelsey A, Egner, John M, Collier, Jack J, Russell, Oliver M, Alston, Charlotte L, Harwig, Megan C, Widlansky, Michael E, Sasorith, Souphatta, Barbosa, Inês A, Douglas, Andrew GL, Baptista, Julia, Walker, Mark, Donnelly, Deirdre E, Morris, Andrew A, Tan, Hui Jeen, Kurian, Manju A, Gorman, Kathleen, Mordekar, Santosh, Deshpande, Charu, Samanta, Rajib, McFarland, Robert, Hill, R Blake, Taylor, Robert W, Oláhová, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354038/
https://www.ncbi.nlm.nih.gov/pubmed/35914810
http://dx.doi.org/10.26508/lsa.202101284

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