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MMAP-08 CHEMO-REIRRADIATION (NORMOFRACTIONATED VS. HYPOFRACTIONATED) WITH OR WITHOUT BEVACIZUMAB IN RECURRENT ADULT DIFFUSE HIGH-GRADE GLIOMA (COBRA): PHASE III RANDOMIZED CONTROLLED TRIAL WITH A 2 X 2 FACTORIAL DESIGN

BACKGROUND: Adult diffuse high-grade gliomas (HGG) predominantly recur locally despite adequate treatment. At recurrence, salvage chemo-reirradiation (CTRT) provides durable local control with significant risk of symptomatic radionecrosis (RN). Reirradiation (reRT) is delivered using either conventi...

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Detalles Bibliográficos
Autores principales: Baviskar, Yamini, Dasgupta, Archya, Chatterjee, Abhishek, Kanan, Sadhana, Epari, Sridhar, Sahu, Arpita, Puranik, Ameya, Patil, Vijay, Moiyadi, Aliasgar, Gupta, Tejpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354168/
http://dx.doi.org/10.1093/noajnl/vdac078.064