SYST-01 MULTI-INSTITUTIONAL RANDOMIZED TRIAL COMPARING CANCER STEM CELL-TARGETED VS PHYSICIAN-CHOICE TREATMENTS IN PATIENTS WITH RECURRENT HIGH-GRADE GLIOMAS (NCT03632135)

BACKGROUND: Clinical outcomes in patients with recurrent high-grade glioma (HGG) remain poor. Cancer stem cells (CSCs) have been implicated in metastasis, treatment resistance and recurrence of HHGs. We have shown in several clinical studies that anti-CSC-directed therapy provides benefits in many c...

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Detalles Bibliográficos
Autores principales: Sengupta, Soma, Ranjan, Tulika, Yu, Alexander, Howard, Candace, Chen, Ricky, Chaudahary, Rekha, Marko, Nicholas, Aregawi, Darit, Glantz, Michael, Glass, Jon, Green, Richard, Lu-Hemerson, Christine, Mammoser, Aaaron, Moulding, Hugh, Jubelirer, Steven, Schoroeder, Jason, Anderson, Mark, Chow, Frances, Lirette, Seth, Denning, Krista, Alberico, Anthony, Valluri, Jagan, Claudio, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354199/
http://dx.doi.org/10.1093/noajnl/vdac078.080

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