SYST-12 D2C7 CAR: A NOVEL CAR T CELL THAT SIMULTANEOUSLY TARGETS WILDTYPE EGFR AND ITS MUTANT ISOFORM EGFRVIII FOR TREATMENT OF GLIOMA AND BRAIN METASTASES

INTRODUCTION: Chimeric antigen receptor (CAR) T-cells represent a revolutionary class of immunotherapy, achieving considerable success in hematological cancers but generally failing to control solid tumors, including gliomas, partly due to the lack of a ubiquitously-expressed target antigen. In this...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilkinson, Daniel, Ryan, Katherine, Wilson, Joseph, Chandramohan, Vidyalakshmi, Bigner, Darell, Fecci, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354223/
http://dx.doi.org/10.1093/noajnl/vdac078.091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354223/
http://dx.doi.org/10.1093/noajnl/vdac078.091

Ejemplares similares