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Template-Free Assembly of Functional RNAs by Loop-Closing Ligation

[Image: see text] The first ribozymes are thought to have emerged at a time when RNA replication proceeded via nonenzymatic template copying processes. However, functional RNAs have stable folded structures, and such structures are much more difficult to copy than short unstructured RNAs. How can th...

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Detalles Bibliográficos
Autores principales: Wu, Long-Fei, Liu, Ziwei, Roberts, Samuel J., Su, Meng, Szostak, Jack W., Sutherland, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354263/
https://www.ncbi.nlm.nih.gov/pubmed/35880790
http://dx.doi.org/10.1021/jacs.2c05601

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