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Inactivation of multiple human pathogens by Fathhome's dry sanitizer device: Rapid and eco-friendly ozone-based disinfection

SARS-CoV-2 spread rapidly, causing millions of deaths across the globe. As a result, demand for medical supplies and personal protective equipment (PPE) surged and supplies dwindled. Separate entirely, hospital-acquired infections have become commonplace and challenging to treat. To explore the pote...

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Autores principales: Kenneally, Ryan, Lawrence, Quentin, Brydon, Ella, Wan, Kenneth H., Mao, Jian-Hua, Verma, Subhash C., Khazaieli, Amir, Celniker, Susan E., Snijders, Antoine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354387/
https://www.ncbi.nlm.nih.gov/pubmed/35945946
http://dx.doi.org/10.1016/j.medmic.2022.100059
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author Kenneally, Ryan
Lawrence, Quentin
Brydon, Ella
Wan, Kenneth H.
Mao, Jian-Hua
Verma, Subhash C.
Khazaieli, Amir
Celniker, Susan E.
Snijders, Antoine M.
author_facet Kenneally, Ryan
Lawrence, Quentin
Brydon, Ella
Wan, Kenneth H.
Mao, Jian-Hua
Verma, Subhash C.
Khazaieli, Amir
Celniker, Susan E.
Snijders, Antoine M.
author_sort Kenneally, Ryan
collection PubMed
description SARS-CoV-2 spread rapidly, causing millions of deaths across the globe. As a result, demand for medical supplies and personal protective equipment (PPE) surged and supplies dwindled. Separate entirely, hospital-acquired infections have become commonplace and challenging to treat. To explore the potential of novel sterilization techniques, this study evaluated the disinfection efficacy of Fathhome's ozone-based, dry-sanitizing device by dose and time response. Inactivation of human pathogens was tested on non-porous (plastic) surfaces. 95.42–100% inactivation was observed across all types of vegetative microorganisms and 27.36% inactivation of bacterial endospores tested, with no residual ozone detectable after completion. These results strongly support the hypothesis that Fathhome's commercial implementation of gas-based disinfection is suitable for rapid decontamination of a wide variety of pathogens on PPE and other industrially relevant materials.
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spelling pubmed-93543872022-08-05 Inactivation of multiple human pathogens by Fathhome's dry sanitizer device: Rapid and eco-friendly ozone-based disinfection Kenneally, Ryan Lawrence, Quentin Brydon, Ella Wan, Kenneth H. Mao, Jian-Hua Verma, Subhash C. Khazaieli, Amir Celniker, Susan E. Snijders, Antoine M. Med Microecol Article SARS-CoV-2 spread rapidly, causing millions of deaths across the globe. As a result, demand for medical supplies and personal protective equipment (PPE) surged and supplies dwindled. Separate entirely, hospital-acquired infections have become commonplace and challenging to treat. To explore the potential of novel sterilization techniques, this study evaluated the disinfection efficacy of Fathhome's ozone-based, dry-sanitizing device by dose and time response. Inactivation of human pathogens was tested on non-porous (plastic) surfaces. 95.42–100% inactivation was observed across all types of vegetative microorganisms and 27.36% inactivation of bacterial endospores tested, with no residual ozone detectable after completion. These results strongly support the hypothesis that Fathhome's commercial implementation of gas-based disinfection is suitable for rapid decontamination of a wide variety of pathogens on PPE and other industrially relevant materials. The Author(s). Published by Elsevier B.V. 2022-12 2022-08-05 /pmc/articles/PMC9354387/ /pubmed/35945946 http://dx.doi.org/10.1016/j.medmic.2022.100059 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kenneally, Ryan
Lawrence, Quentin
Brydon, Ella
Wan, Kenneth H.
Mao, Jian-Hua
Verma, Subhash C.
Khazaieli, Amir
Celniker, Susan E.
Snijders, Antoine M.
Inactivation of multiple human pathogens by Fathhome's dry sanitizer device: Rapid and eco-friendly ozone-based disinfection
title Inactivation of multiple human pathogens by Fathhome's dry sanitizer device: Rapid and eco-friendly ozone-based disinfection
title_full Inactivation of multiple human pathogens by Fathhome's dry sanitizer device: Rapid and eco-friendly ozone-based disinfection
title_fullStr Inactivation of multiple human pathogens by Fathhome's dry sanitizer device: Rapid and eco-friendly ozone-based disinfection
title_full_unstemmed Inactivation of multiple human pathogens by Fathhome's dry sanitizer device: Rapid and eco-friendly ozone-based disinfection
title_short Inactivation of multiple human pathogens by Fathhome's dry sanitizer device: Rapid and eco-friendly ozone-based disinfection
title_sort inactivation of multiple human pathogens by fathhome's dry sanitizer device: rapid and eco-friendly ozone-based disinfection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354387/
https://www.ncbi.nlm.nih.gov/pubmed/35945946
http://dx.doi.org/10.1016/j.medmic.2022.100059
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