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Comprehensive geriatric assessment for older orthopedic patients and analysis of risk factors for postoperative complications

BACKGROUND: The comprehensive geriatric assessment (CGA) has been proposed as a supplementary tool to reduce perioperative complications of geriatric patients, however there is no universally accepted standardization of CGA for orthopedic surgery. In this study, a novel CGA strategy was applied to e...

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Autores principales: Kong, Chao, Zhang, Yanhong, Wang, Chaodong, Wang, Peng, Li, Xiangyu, Wang, Wei, Wang, Yu, Shen, Jianghua, Ren, Xiaoyi, Wang, Tianlong, Zhao, Guoguang, Lu, Shibao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354431/
https://www.ncbi.nlm.nih.gov/pubmed/35927629
http://dx.doi.org/10.1186/s12877-022-03328-5
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author Kong, Chao
Zhang, Yanhong
Wang, Chaodong
Wang, Peng
Li, Xiangyu
Wang, Wei
Wang, Yu
Shen, Jianghua
Ren, Xiaoyi
Wang, Tianlong
Zhao, Guoguang
Lu, Shibao
author_facet Kong, Chao
Zhang, Yanhong
Wang, Chaodong
Wang, Peng
Li, Xiangyu
Wang, Wei
Wang, Yu
Shen, Jianghua
Ren, Xiaoyi
Wang, Tianlong
Zhao, Guoguang
Lu, Shibao
author_sort Kong, Chao
collection PubMed
description BACKGROUND: The comprehensive geriatric assessment (CGA) has been proposed as a supplementary tool to reduce perioperative complications of geriatric patients, however there is no universally accepted standardization of CGA for orthopedic surgery. In this study, a novel CGA strategy was applied to evaluate the conditions of older patients undergoing orthopedic surgery from a broad view and to identify potential risk factors for postoperative complications. METHODS: A prospective cohort study was conducted from March 2019 to December 2020.The study enrolled patients (age > 75 years) for elective or confined orthopedic surgery. All patients were treated by a multidisciplinary team. A structured CGA was conducted to identify high-risk older patients and to facilitate coordinated multidisciplinary team care by a geriatric team. The basic patient characteristics, CGA results, postoperative complication and mortality rates were collected. Multivariate logistic regression analysis was used to identify risk factors for postoperative complications. RESULTS: A total of 214 patients with an age of 81.07 ± 4.78 (range, 75–100) years were prospectively enrolled in this study. In total, 66 (30.8%) complications were registered, including one death from myocardial infarction (mortality rate, 0.5%). Poor Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) were accompanied by frailty, worse perioperative risk, pain, and nutritional status. Poor ADL was also associated with higher risks of falling, polypharmacy, and cardiac and respiration complications. Poor IADL was associated with a higher risk of cardiac and respiration complications. Higher stroke risk was accompanied by higher risks of cardiac complications, delirium, and hemorrhage. Worse American Society of Anesthesiologists (ASA) score was associated with worse ADL, IADL, frailty, and higher delirium risk. Multivariate logistic regression analysis showed that spinal fusion (odds ratio [OR], 0.73; 95% confidence interval [CI], 0.65 to 0.83; p = 0.0214), blood loss(OR, 1.68; 95% CI, 1.31 to 2.01; p = 0.0168), ADL (severe dysfunction or worse) (OR, 1.45; 95% CI, 1.16 to 1.81; p = 0.0413), IADL (serious dependence) (OR, 1.08; 95% CI, 1.33 to 1.63; p = 0.0436), renal function (chronic kidney disease (CKD) ≥ stage 3a) (OR, 2.01; 95% CI, 1.54 to 2.55; p = 0.0133), and malnutrition(OR, 2.11; 95% CI, 1.74 to 2.56; p = 0.0101) were independent risk factors for postoperative complications. CONCLUSION: The CGA process reduces patient mortality and increases safety in older orthopedic surgery patients. Spinal fusion, blood loss, ADL (severe dysfunction or worse), IADL (serious dependence), renal function (CKD ≥ stage 3a) and nutrition mini nutritional assessment (MNA) (malnourished) were independent risk factors of postoperative complications following orthopaedic surgery in older patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-022-03328-5.
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spelling pubmed-93544312022-08-06 Comprehensive geriatric assessment for older orthopedic patients and analysis of risk factors for postoperative complications Kong, Chao Zhang, Yanhong Wang, Chaodong Wang, Peng Li, Xiangyu Wang, Wei Wang, Yu Shen, Jianghua Ren, Xiaoyi Wang, Tianlong Zhao, Guoguang Lu, Shibao BMC Geriatr Research BACKGROUND: The comprehensive geriatric assessment (CGA) has been proposed as a supplementary tool to reduce perioperative complications of geriatric patients, however there is no universally accepted standardization of CGA for orthopedic surgery. In this study, a novel CGA strategy was applied to evaluate the conditions of older patients undergoing orthopedic surgery from a broad view and to identify potential risk factors for postoperative complications. METHODS: A prospective cohort study was conducted from March 2019 to December 2020.The study enrolled patients (age > 75 years) for elective or confined orthopedic surgery. All patients were treated by a multidisciplinary team. A structured CGA was conducted to identify high-risk older patients and to facilitate coordinated multidisciplinary team care by a geriatric team. The basic patient characteristics, CGA results, postoperative complication and mortality rates were collected. Multivariate logistic regression analysis was used to identify risk factors for postoperative complications. RESULTS: A total of 214 patients with an age of 81.07 ± 4.78 (range, 75–100) years were prospectively enrolled in this study. In total, 66 (30.8%) complications were registered, including one death from myocardial infarction (mortality rate, 0.5%). Poor Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) were accompanied by frailty, worse perioperative risk, pain, and nutritional status. Poor ADL was also associated with higher risks of falling, polypharmacy, and cardiac and respiration complications. Poor IADL was associated with a higher risk of cardiac and respiration complications. Higher stroke risk was accompanied by higher risks of cardiac complications, delirium, and hemorrhage. Worse American Society of Anesthesiologists (ASA) score was associated with worse ADL, IADL, frailty, and higher delirium risk. Multivariate logistic regression analysis showed that spinal fusion (odds ratio [OR], 0.73; 95% confidence interval [CI], 0.65 to 0.83; p = 0.0214), blood loss(OR, 1.68; 95% CI, 1.31 to 2.01; p = 0.0168), ADL (severe dysfunction or worse) (OR, 1.45; 95% CI, 1.16 to 1.81; p = 0.0413), IADL (serious dependence) (OR, 1.08; 95% CI, 1.33 to 1.63; p = 0.0436), renal function (chronic kidney disease (CKD) ≥ stage 3a) (OR, 2.01; 95% CI, 1.54 to 2.55; p = 0.0133), and malnutrition(OR, 2.11; 95% CI, 1.74 to 2.56; p = 0.0101) were independent risk factors for postoperative complications. CONCLUSION: The CGA process reduces patient mortality and increases safety in older orthopedic surgery patients. Spinal fusion, blood loss, ADL (severe dysfunction or worse), IADL (serious dependence), renal function (CKD ≥ stage 3a) and nutrition mini nutritional assessment (MNA) (malnourished) were independent risk factors of postoperative complications following orthopaedic surgery in older patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-022-03328-5. BioMed Central 2022-08-04 /pmc/articles/PMC9354431/ /pubmed/35927629 http://dx.doi.org/10.1186/s12877-022-03328-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Kong, Chao
Zhang, Yanhong
Wang, Chaodong
Wang, Peng
Li, Xiangyu
Wang, Wei
Wang, Yu
Shen, Jianghua
Ren, Xiaoyi
Wang, Tianlong
Zhao, Guoguang
Lu, Shibao
Comprehensive geriatric assessment for older orthopedic patients and analysis of risk factors for postoperative complications
title Comprehensive geriatric assessment for older orthopedic patients and analysis of risk factors for postoperative complications
title_full Comprehensive geriatric assessment for older orthopedic patients and analysis of risk factors for postoperative complications
title_fullStr Comprehensive geriatric assessment for older orthopedic patients and analysis of risk factors for postoperative complications
title_full_unstemmed Comprehensive geriatric assessment for older orthopedic patients and analysis of risk factors for postoperative complications
title_short Comprehensive geriatric assessment for older orthopedic patients and analysis of risk factors for postoperative complications
title_sort comprehensive geriatric assessment for older orthopedic patients and analysis of risk factors for postoperative complications
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354431/
https://www.ncbi.nlm.nih.gov/pubmed/35927629
http://dx.doi.org/10.1186/s12877-022-03328-5
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