Targeted Deletion of the Claudin12 Gene in Mice Increases Articular Cartilage and Inhibits Chondrocyte Differentiation

To study the role of Claudin (CLDN)12 in bone, we developed mice with a targeted deletion of exon2 in the Cldn12 gene for skeletal phenotype analysis. Micro-CT analysis of the secondary spongiosa of distal femurs of mice with targeted disruption of the Cldn12 gene and control littermates showed no s...

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Detalles Bibliográficos
Autores principales: Xing, Weirong, Pourteymoor, Sheila, Chen, Yian, Mohan, Subburaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354527/
https://www.ncbi.nlm.nih.gov/pubmed/35937800
http://dx.doi.org/10.3389/fendo.2022.931318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354527/
https://www.ncbi.nlm.nih.gov/pubmed/35937800
http://dx.doi.org/10.3389/fendo.2022.931318

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