Heterologous production of the adhesin LIC13411 from pathogenic Leptospira facilitates binding of non-pathogenic Leptospira in vitro and in vivo

Leptospirosis is an important cause of morbidity and mortality worldwide. Disease severity ranges from asymptomatic colonization to widespread hemorrhage and multiorgan dysfunction. The causative agents, Leptospira spp., are zoonotic Gram-negative spirochetes. One important step in pathogenesis is b...

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Detalles Bibliográficos
Autores principales: Surdel, Matthew C., Hahn, Beth L., Anderson, Phillip N., Coburn, Jenifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354625/
https://www.ncbi.nlm.nih.gov/pubmed/35937702
http://dx.doi.org/10.3389/fcimb.2022.917963

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