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The R.E.N.A.L score’s relevance in determining perioperative and oncological outcomes: a Middle-Eastern tertiary care center experience
OBJECTIVE: The aim of this study is to evaluate the significance of the R.E.N.A.L nephrometry scoring system in predicting perioperative and oncological outcomes and determining the surgical approach of choice for kidney tumors. Patients and Methods: Our study retrospectively reviewed outcomes from...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354629/ https://www.ncbi.nlm.nih.gov/pubmed/35935911 http://dx.doi.org/10.1080/2090598X.2022.2064041 |
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author | Abou Heidar, Nassib Hakam, Nizar El-Asmar, Jose M Najdi, Jad Khauli, Mark A. Degheili, Jad El-Hajj, Albert Nasr, Rami Wazzan, Wassim Bulbul, Muhammad Mukherji, Deborah Khauli, Raja |
author_facet | Abou Heidar, Nassib Hakam, Nizar El-Asmar, Jose M Najdi, Jad Khauli, Mark A. Degheili, Jad El-Hajj, Albert Nasr, Rami Wazzan, Wassim Bulbul, Muhammad Mukherji, Deborah Khauli, Raja |
author_sort | Abou Heidar, Nassib |
collection | PubMed |
description | OBJECTIVE: The aim of this study is to evaluate the significance of the R.E.N.A.L nephrometry scoring system in predicting perioperative and oncological outcomes and determining the surgical approach of choice for kidney tumors. Patients and Methods: Our study retrospectively reviewed outcomes from the year 2002 to 2017. Mann-Whitney U test was used to compare continuous variables and chi-square test was used to compare categorical variables. Kaplan-Meier estimates and multivariable cox proportional hazard regression were performed to determine an association between the different R.E.N.A.L categories and disease recurrence or mortality. RESULTS: A total of 325 patients underwent kidney surgery The most common R.E.N.A.L score category in our cohort study was intermediate (41.2%), followed by low, (33.2%) and high (25.5%). Patients with a high R.E.N.A.L score had worse perioperative outcomes compared to those with a low R.E.N.A.L score. High R.E.N.A.L score patients were 3 times more likely to receive blood transfusions compared to those with a low R.E.N.A.L score (19.4% vs 6.3%, p = 0.018), and a statistically significant longer hospital length of stay was also observed between the two groups (median 4.5 vs 4 days, p = 0.0419). In addition, the only predictor of disease recurrence or mortality was a high R.E.N.A.L score (Hazard Ratio (HR) 3.65, 95% Confidence Interval (CI) 1.05–12.7, p = 0.041). CONCLUSION: Our study sheds light on the use of R.E.N.A.L nephrometry score in predicting perioperative, postoperative, and oncological outcomes. Such findings may play a role in optimizing surgical approaches and pre-operative patient counseling. |
format | Online Article Text |
id | pubmed-9354629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-93546292022-08-06 The R.E.N.A.L score’s relevance in determining perioperative and oncological outcomes: a Middle-Eastern tertiary care center experience Abou Heidar, Nassib Hakam, Nizar El-Asmar, Jose M Najdi, Jad Khauli, Mark A. Degheili, Jad El-Hajj, Albert Nasr, Rami Wazzan, Wassim Bulbul, Muhammad Mukherji, Deborah Khauli, Raja Arab J Urol Research Article OBJECTIVE: The aim of this study is to evaluate the significance of the R.E.N.A.L nephrometry scoring system in predicting perioperative and oncological outcomes and determining the surgical approach of choice for kidney tumors. Patients and Methods: Our study retrospectively reviewed outcomes from the year 2002 to 2017. Mann-Whitney U test was used to compare continuous variables and chi-square test was used to compare categorical variables. Kaplan-Meier estimates and multivariable cox proportional hazard regression were performed to determine an association between the different R.E.N.A.L categories and disease recurrence or mortality. RESULTS: A total of 325 patients underwent kidney surgery The most common R.E.N.A.L score category in our cohort study was intermediate (41.2%), followed by low, (33.2%) and high (25.5%). Patients with a high R.E.N.A.L score had worse perioperative outcomes compared to those with a low R.E.N.A.L score. High R.E.N.A.L score patients were 3 times more likely to receive blood transfusions compared to those with a low R.E.N.A.L score (19.4% vs 6.3%, p = 0.018), and a statistically significant longer hospital length of stay was also observed between the two groups (median 4.5 vs 4 days, p = 0.0419). In addition, the only predictor of disease recurrence or mortality was a high R.E.N.A.L score (Hazard Ratio (HR) 3.65, 95% Confidence Interval (CI) 1.05–12.7, p = 0.041). CONCLUSION: Our study sheds light on the use of R.E.N.A.L nephrometry score in predicting perioperative, postoperative, and oncological outcomes. Such findings may play a role in optimizing surgical approaches and pre-operative patient counseling. Taylor & Francis 2022-04-17 /pmc/articles/PMC9354629/ /pubmed/35935911 http://dx.doi.org/10.1080/2090598X.2022.2064041 Text en © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Abou Heidar, Nassib Hakam, Nizar El-Asmar, Jose M Najdi, Jad Khauli, Mark A. Degheili, Jad El-Hajj, Albert Nasr, Rami Wazzan, Wassim Bulbul, Muhammad Mukherji, Deborah Khauli, Raja The R.E.N.A.L score’s relevance in determining perioperative and oncological outcomes: a Middle-Eastern tertiary care center experience |
title | The R.E.N.A.L score’s relevance in determining perioperative and oncological outcomes: a Middle-Eastern tertiary care center experience |
title_full | The R.E.N.A.L score’s relevance in determining perioperative and oncological outcomes: a Middle-Eastern tertiary care center experience |
title_fullStr | The R.E.N.A.L score’s relevance in determining perioperative and oncological outcomes: a Middle-Eastern tertiary care center experience |
title_full_unstemmed | The R.E.N.A.L score’s relevance in determining perioperative and oncological outcomes: a Middle-Eastern tertiary care center experience |
title_short | The R.E.N.A.L score’s relevance in determining perioperative and oncological outcomes: a Middle-Eastern tertiary care center experience |
title_sort | r.e.n.a.l score’s relevance in determining perioperative and oncological outcomes: a middle-eastern tertiary care center experience |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354629/ https://www.ncbi.nlm.nih.gov/pubmed/35935911 http://dx.doi.org/10.1080/2090598X.2022.2064041 |
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