The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation

The phosphoinositide 3–kinase (PI3K) pathway regulates proliferation, survival, and metabolism and is frequently activated across human cancers. A comprehensive elucidation of how this signaling pathway controls transcriptional and cotranscriptional processes could provide new insights into the key...

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Detalles Bibliográficos
Autores principales: Ladewig, Erik, Michelini, Flavia, Jhaveri, Komal, Castel, Pau, Carmona, Javier, Fairchild, Lauren, Zuniga, Adler G., Arruabarrena-Aristorena, Amaia, Cocco, Emiliano, Blawski, Ryan, Kittane, Srushti, Zhang, Yuhan, Sallaku, Mirna, Baldino, Laura, Hristidis, Vasilis, Chandarlapaty, Sarat, Abdel-Wahab, Omar, Leslie, Christina, Scaltriti, Maurizio, Toska, Eneda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Tumor Biology and Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354703/
https://www.ncbi.nlm.nih.gov/pubmed/35442400
http://dx.doi.org/10.1158/0008-5472.CAN-22-0446

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