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Neuroprotective Properties of Bis-Sulfonamide Derivatives Against 6-OHDA-Induced Parkinson's Model via Sirtuin 1 Activity and in silico Pharmacokinetic Properties

Parkinson's disease (PD) is considered one of the health problems in the aging society. Due to the limitations of currently available drugs in preventing disease progression, the discovery of novel neuroprotective agents has been challenged. Sulfonamide and its derivatives were reported for sev...

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Detalles Bibliográficos
Autores principales: Apiraksattayakul, Setthawut, Pingaew, Ratchanok, Prachayasittikul, Veda, Ruankham, Waralee, Jongwachirachai, Papitcha, Songtawee, Napat, Suwanjang, Wilasinee, Tantimongcolwat, Tanawut, Prachayasittikul, Supaluk, Prachayasittikul, Virapong, Phopin, Kamonrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354714/
https://www.ncbi.nlm.nih.gov/pubmed/35935335
http://dx.doi.org/10.3389/fnmol.2022.890838