Cargando…
Vaginal microecological characteristics of women in different physiological and pathological period
The vaginal microbiota, the host endocrine system, the vaginal anatomy, and the local mucosal immunity comprise the vaginal microbiota, which interacts with each other to maintain the balance of the vaginal microbiota, which maintains female reproductive health. Puberty, menstruation, pregnancy, and...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354832/ https://www.ncbi.nlm.nih.gov/pubmed/35937699 http://dx.doi.org/10.3389/fcimb.2022.959793 |
_version_ | 1784763158475309056 |
---|---|
author | Shen, Liping Zhang, Wei Yuan, Yi Zhu, Weipei Shang, Anquan |
author_facet | Shen, Liping Zhang, Wei Yuan, Yi Zhu, Weipei Shang, Anquan |
author_sort | Shen, Liping |
collection | PubMed |
description | The vaginal microbiota, the host endocrine system, the vaginal anatomy, and the local mucosal immunity comprise the vaginal microbiota, which interacts with each other to maintain the balance of the vaginal microbiota, which maintains female reproductive health. Puberty, menstruation, pregnancy, and menopause are four phases women go through during their reproductive and post-reproductive years. Vaginal microbiota composition and abundance are heavily influenced by estrogen and progesterone, which start at puberty and continue during the reproductive years in a dynamic balance with some fluctuations. Estrogen promotes proliferation of vaginal epithelial cells and increases glycogen storage, while progesterone lyses vaginal epithelial cells, facilitating the release of glycogen to maintain normal pH. This review summarizes the latest national and international evidence on the composition and distribution of vaginal microecology in women during different physiological and pathological periods and proposes a hormone-driven microbial diversity hypothesis to explain the temporal patterns of vaginal microbial diversity during the female reproductive cycle and menopause. A relatively balanced vaginal microecological system has a positive effect on the maintenance of female health. An imbalance in the ratio of flora can lead to susceptibility to infections or reproductive complications. The study of human microecology and its role in the development and progression of human disease is essential for the prevention, diagnosis, and treatment of related obstetric and gynecologic conditions. |
format | Online Article Text |
id | pubmed-9354832 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93548322022-08-06 Vaginal microecological characteristics of women in different physiological and pathological period Shen, Liping Zhang, Wei Yuan, Yi Zhu, Weipei Shang, Anquan Front Cell Infect Microbiol Cellular and Infection Microbiology The vaginal microbiota, the host endocrine system, the vaginal anatomy, and the local mucosal immunity comprise the vaginal microbiota, which interacts with each other to maintain the balance of the vaginal microbiota, which maintains female reproductive health. Puberty, menstruation, pregnancy, and menopause are four phases women go through during their reproductive and post-reproductive years. Vaginal microbiota composition and abundance are heavily influenced by estrogen and progesterone, which start at puberty and continue during the reproductive years in a dynamic balance with some fluctuations. Estrogen promotes proliferation of vaginal epithelial cells and increases glycogen storage, while progesterone lyses vaginal epithelial cells, facilitating the release of glycogen to maintain normal pH. This review summarizes the latest national and international evidence on the composition and distribution of vaginal microecology in women during different physiological and pathological periods and proposes a hormone-driven microbial diversity hypothesis to explain the temporal patterns of vaginal microbial diversity during the female reproductive cycle and menopause. A relatively balanced vaginal microecological system has a positive effect on the maintenance of female health. An imbalance in the ratio of flora can lead to susceptibility to infections or reproductive complications. The study of human microecology and its role in the development and progression of human disease is essential for the prevention, diagnosis, and treatment of related obstetric and gynecologic conditions. Frontiers Media S.A. 2022-07-22 /pmc/articles/PMC9354832/ /pubmed/35937699 http://dx.doi.org/10.3389/fcimb.2022.959793 Text en Copyright © 2022 Shen, Zhang, Yuan, Zhu and Shang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cellular and Infection Microbiology Shen, Liping Zhang, Wei Yuan, Yi Zhu, Weipei Shang, Anquan Vaginal microecological characteristics of women in different physiological and pathological period |
title | Vaginal microecological characteristics of women in different physiological and pathological period |
title_full | Vaginal microecological characteristics of women in different physiological and pathological period |
title_fullStr | Vaginal microecological characteristics of women in different physiological and pathological period |
title_full_unstemmed | Vaginal microecological characteristics of women in different physiological and pathological period |
title_short | Vaginal microecological characteristics of women in different physiological and pathological period |
title_sort | vaginal microecological characteristics of women in different physiological and pathological period |
topic | Cellular and Infection Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354832/ https://www.ncbi.nlm.nih.gov/pubmed/35937699 http://dx.doi.org/10.3389/fcimb.2022.959793 |
work_keys_str_mv | AT shenliping vaginalmicroecologicalcharacteristicsofwomenindifferentphysiologicalandpathologicalperiod AT zhangwei vaginalmicroecologicalcharacteristicsofwomenindifferentphysiologicalandpathologicalperiod AT yuanyi vaginalmicroecologicalcharacteristicsofwomenindifferentphysiologicalandpathologicalperiod AT zhuweipei vaginalmicroecologicalcharacteristicsofwomenindifferentphysiologicalandpathologicalperiod AT shanganquan vaginalmicroecologicalcharacteristicsofwomenindifferentphysiologicalandpathologicalperiod |