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Neonatal Sepsis and Associated Factors Among Newborns in Woldia and Dessie Comprehensive Specialized Hospitals, North-East Ethiopia, 2021
INTRODUCTION: Neonatal sepsis is a clinical illness characterized by infection-related signs and symptoms in the first month of life, with or without bacteremia. Septicemia, meningitis, pneumonia, arthritis, osteomyelitis, and urinary tract infections are all examples of systemic illnesses that can...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354861/ https://www.ncbi.nlm.nih.gov/pubmed/35937781 http://dx.doi.org/10.2147/IDR.S374835 |
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author | Birrie, Endalk Sisay, Ermias Tibebu, Nigusie Selomon Tefera, Birhanu Desu Zeleke, Mulusew Tefera, Zenebe |
author_facet | Birrie, Endalk Sisay, Ermias Tibebu, Nigusie Selomon Tefera, Birhanu Desu Zeleke, Mulusew Tefera, Zenebe |
author_sort | Birrie, Endalk |
collection | PubMed |
description | INTRODUCTION: Neonatal sepsis is a clinical illness characterized by infection-related signs and symptoms in the first month of life, with or without bacteremia. Septicemia, meningitis, pneumonia, arthritis, osteomyelitis, and urinary tract infections are all examples of systemic illnesses that can affect newborns. Hence, the main aim of this study was to assess the prevalence and factors associated with neonatal sepsis among newborns in Woldia and Dessie Comprehensive Specialized Hospitals, northeast Ethiopia, from January 1 to July 30, 2021. METHODS: This institution-based cross-sectional study was conducted from January 1 to July 30, 2021, on 344 randomly selected neonates who visited the hospital. A systematic random sampling technique was used to select samples, and data were collected using a pre-tested standardized questionnaire. For data entry and analysis, Epi Data version 4.1 and SPSS version 24 applications were used, respectively. The goodness-of-fit was tested by the Hosmer–Lemeshow statistic test. Bivariable and multivariable binary logistic regressions were used to identify associated factors at a 95% confidence interval. Significance was considered at p-value <0.05. RESULTS: In this study, the prevalence of neonatal sepsis was 79.4% (95% CI: 75.2–83.6%). Maternal UTI/STI history [AOR: 3.1; 95% CI (1.5–7.1)], gestational age <37 weeks [AOR: 4.4; 95% CI (1.0–8.9)], PROM [AOR: 4.9; 95% CI (2.5–6.8)], and new-born resuscitation history [AOR: 2.3; 95% CI (1.5–4.3)] were all significantly associated with neonatal sepsis. CONCLUSION: This study indicates that the proportion of neonatal sepsis is high. A history of maternal PROM, being a preterm neonate, a history of maternal UTI/STIs, and having received resuscitation at birth were identified as risk factors for neonatal sepsis. |
format | Online Article Text |
id | pubmed-9354861 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-93548612022-08-06 Neonatal Sepsis and Associated Factors Among Newborns in Woldia and Dessie Comprehensive Specialized Hospitals, North-East Ethiopia, 2021 Birrie, Endalk Sisay, Ermias Tibebu, Nigusie Selomon Tefera, Birhanu Desu Zeleke, Mulusew Tefera, Zenebe Infect Drug Resist Original Research INTRODUCTION: Neonatal sepsis is a clinical illness characterized by infection-related signs and symptoms in the first month of life, with or without bacteremia. Septicemia, meningitis, pneumonia, arthritis, osteomyelitis, and urinary tract infections are all examples of systemic illnesses that can affect newborns. Hence, the main aim of this study was to assess the prevalence and factors associated with neonatal sepsis among newborns in Woldia and Dessie Comprehensive Specialized Hospitals, northeast Ethiopia, from January 1 to July 30, 2021. METHODS: This institution-based cross-sectional study was conducted from January 1 to July 30, 2021, on 344 randomly selected neonates who visited the hospital. A systematic random sampling technique was used to select samples, and data were collected using a pre-tested standardized questionnaire. For data entry and analysis, Epi Data version 4.1 and SPSS version 24 applications were used, respectively. The goodness-of-fit was tested by the Hosmer–Lemeshow statistic test. Bivariable and multivariable binary logistic regressions were used to identify associated factors at a 95% confidence interval. Significance was considered at p-value <0.05. RESULTS: In this study, the prevalence of neonatal sepsis was 79.4% (95% CI: 75.2–83.6%). Maternal UTI/STI history [AOR: 3.1; 95% CI (1.5–7.1)], gestational age <37 weeks [AOR: 4.4; 95% CI (1.0–8.9)], PROM [AOR: 4.9; 95% CI (2.5–6.8)], and new-born resuscitation history [AOR: 2.3; 95% CI (1.5–4.3)] were all significantly associated with neonatal sepsis. CONCLUSION: This study indicates that the proportion of neonatal sepsis is high. A history of maternal PROM, being a preterm neonate, a history of maternal UTI/STIs, and having received resuscitation at birth were identified as risk factors for neonatal sepsis. Dove 2022-08-01 /pmc/articles/PMC9354861/ /pubmed/35937781 http://dx.doi.org/10.2147/IDR.S374835 Text en © 2022 Birrie et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Birrie, Endalk Sisay, Ermias Tibebu, Nigusie Selomon Tefera, Birhanu Desu Zeleke, Mulusew Tefera, Zenebe Neonatal Sepsis and Associated Factors Among Newborns in Woldia and Dessie Comprehensive Specialized Hospitals, North-East Ethiopia, 2021 |
title | Neonatal Sepsis and Associated Factors Among Newborns in Woldia and Dessie Comprehensive Specialized Hospitals, North-East Ethiopia, 2021 |
title_full | Neonatal Sepsis and Associated Factors Among Newborns in Woldia and Dessie Comprehensive Specialized Hospitals, North-East Ethiopia, 2021 |
title_fullStr | Neonatal Sepsis and Associated Factors Among Newborns in Woldia and Dessie Comprehensive Specialized Hospitals, North-East Ethiopia, 2021 |
title_full_unstemmed | Neonatal Sepsis and Associated Factors Among Newborns in Woldia and Dessie Comprehensive Specialized Hospitals, North-East Ethiopia, 2021 |
title_short | Neonatal Sepsis and Associated Factors Among Newborns in Woldia and Dessie Comprehensive Specialized Hospitals, North-East Ethiopia, 2021 |
title_sort | neonatal sepsis and associated factors among newborns in woldia and dessie comprehensive specialized hospitals, north-east ethiopia, 2021 |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354861/ https://www.ncbi.nlm.nih.gov/pubmed/35937781 http://dx.doi.org/10.2147/IDR.S374835 |
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