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IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation

Regulation of innate immune responses is essential for maintenance of immune homeostasis and development of an appropriate immunity against microbial infection. We show here that miR-3614-5p, product of the TRIM25 host gene, is induced by type I interferon (IFN-I) in several human non-immune and imm...

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Detalles Bibliográficos
Autores principales: Vuillier, Françoise, Li, Zhi, Black, Iain, Cruciani, Melania, Rubino, Erminia, Michel, Frédérique, Pellegrini, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354889/
https://www.ncbi.nlm.nih.gov/pubmed/35935998
http://dx.doi.org/10.3389/fimmu.2022.939907