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Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation

Hemolysis, as a result of disease or exposure to biomaterials, is characterized by excess amounts of cell-free heme intravascularly and consumption of the protective heme-scavenger proteins in plasma. The liberation of heme has been linked to the activation of inflammatory systems, including the com...

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Detalles Bibliográficos
Autores principales:	Gerogianni, Alexandra, Dimitrov, Jordan D., Zarantonello, Alessandra, Poillerat, Victoria, Chonat, Satheesh, Sandholm, Kerstin, McAdam, Karin E., Ekdahl, Kristina N., Mollnes, Tom E., Mohlin, Camilla, Roumenina, Lubka T., Nilsson, Per H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354932/ https://www.ncbi.nlm.nih.gov/pubmed/35935964 http://dx.doi.org/10.3389/fimmu.2022.901876

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