Class IIa histone deacetylase inhibition ameliorates acute kidney injury by suppressing renal tubular cell apoptosis and enhancing autophagy and proliferation

Expression and function of histone deacetylases (HDACs) vary with cell types and pathological conditions. Our recent studies showed that pharmacological targeting class IIa HDACs attenuated renal fibrosis, but the effect of class IIa HDAC inhibition on acute kidney injury (AKI) remains unknown. In t...

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Detalles Bibliográficos
Autores principales: Li, Jialu, Yu, Chao, Shen, Fengchen, Cui, Binbin, Liu, Na, Zhuang, Shougang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354984/
https://www.ncbi.nlm.nih.gov/pubmed/35935816
http://dx.doi.org/10.3389/fphar.2022.946192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354984/
https://www.ncbi.nlm.nih.gov/pubmed/35935816
http://dx.doi.org/10.3389/fphar.2022.946192

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