Cargando…

Class IIa histone deacetylase inhibition ameliorates acute kidney injury by suppressing renal tubular cell apoptosis and enhancing autophagy and proliferation

Expression and function of histone deacetylases (HDACs) vary with cell types and pathological conditions. Our recent studies showed that pharmacological targeting class IIa HDACs attenuated renal fibrosis, but the effect of class IIa HDAC inhibition on acute kidney injury (AKI) remains unknown. In t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jialu, Yu, Chao, Shen, Fengchen, Cui, Binbin, Liu, Na, Zhuang, Shougang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354984/ https://www.ncbi.nlm.nih.gov/pubmed/35935816 http://dx.doi.org/10.3389/fphar.2022.946192

Ejemplares similares

Histone Acetylation and Modifiers in Renal Fibrosis
por: Shen, Fengchen, et al.
Publicado: (2022)

The Role and Mechanism of Histone Deacetylases in Acute Kidney Injury
por: Zhou, Xun, et al.
Publicado: (2021)

Design of Diarylheptanoid Derivatives as Dual Inhibitors Against Class IIa Histone Deacetylase and β-amyloid Aggregation
por: Chen, Liang-Chieh, et al.
Publicado: (2018)

Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury
por: He, Xu, et al.
Publicado: (2022)

Requirement of Histone Deacetylase 6 for Interleukin-6 Induced Epithelial-Mesenchymal Transition, Proliferation, and Migration of Peritoneal Mesothelial Cells
por: Shi, Yingfeng, et al.
Publicado: (2021)

Class IIa Histone Deacetylases Are Conserved Regulators of Circadian Function
por: Fogg, Paul C. M., et al.
Publicado: (2014)

The role of class IIa histone deacetylases in regulating endothelial function
por: Shen, Zexu, et al.
Publicado: (2023)

Roles and Targets of Class I and IIa Histone Deacetylases in Cardiac Hypertrophy
por: Kee, Hae Jin, et al.
Publicado: (2011)

Treatment of chronic kidney diseases with histone deacetylase inhibitors
por: Liu, Na, et al.
Publicado: (2015)

Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogramming
por: Luo, Zhiwei, et al.
Publicado: (2019)

Roles and post-translational regulation of cardiac class IIa histone deacetylase isoforms
por: Weeks, Kate L, et al.
Publicado: (2015)

Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation
por: Zhou, Hongyi, et al.
Publicado: (2021)

Blocking the Class I Histone Deacetylase Ameliorates Renal Fibrosis and Inhibits Renal Fibroblast Activation via Modulating TGF-Beta and EGFR Signaling
por: Liu, Na, et al.
Publicado: (2013)

Histone Methyltransferases as Therapeutic Targets for Kidney Diseases
por: Yu, Chao, et al.
Publicado: (2019)

Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4
por: Zhao, Yu Tina, et al.
Publicado: (2016)

Histone Modifications in Acute Kidney Injury
por: Wang, Jun, et al.
Publicado: (2022)

Novel Histone Deacetylase Class IIa Selective Substrate Radiotracers for PET Imaging of Epigenetic Regulation in the Brain
por: Bonomi, Robin, et al.
Publicado: (2015)

Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex
por: Hudson, Gregg M., et al.
Publicado: (2015)

Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells
por: Gomis-Coloma, Clara, et al.
Publicado: (2018)

Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach
por: Hsu, Kai-Cheng, et al.
Publicado: (2017)

Pharmacological and Genetic Inhibition of HDAC4 Alleviates Renal Injury and Fibrosis in Mice
por: Shen, Fengchen, et al.
Publicado: (2022)

The Novel Class IIa Selective Histone Deacetylase Inhibitor YAK540 Is Synergistic with Bortezomib in Leukemia Cell Lines
por: Bollmann, Lukas M., et al.
Publicado: (2022)

Carbocisteine Improves Histone Deacetylase 2 Deacetylation Activity via Regulating Sumoylation of Histone Deacetylase 2 in Human Tracheobronchial Epithelial Cells
por: Song, Yun, et al.
Publicado: (2019)

Natural Products Impacting DNA Methyltransferases and Histone Deacetylases
por: Akone, Sergi Herve, et al.
Publicado: (2020)

Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4
por: Wang, Yangmeng, et al.
Publicado: (2017)

Evaluation of Class IIa Histone Deacetylases Expression and In Vivo Epigenetic Imaging in a Transgenic Mouse Model of Alzheimer’s Disease
por: Chen, Yi-An, et al.
Publicado: (2021)

Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy
por: Stankov, Metodi V., et al.
Publicado: (2013)

Tambulin Targets Histone Deacetylase 1 Inhibiting Cell Growth and Inducing Apoptosis in Human Lung Squamous Cell Carcinoma
por: Wang, Wuming, et al.
Publicado: (2020)

Histone Deacetylases Inhibitors in Neurodegenerative Diseases, Neuroprotection and Neuronal Differentiation
por: Shukla, Surabhi, et al.
Publicado: (2020)

Tricaproin Isolated From Simarouba glauca Inhibits the Growth of Human Colorectal Carcinoma Cell Lines by Targeting Class-1 Histone Deacetylases
por: Jose, Asha, et al.
Publicado: (2018)

Correlation analysis between expression of histone deacetylase 6 and clinical parameters in IgA nephropathy patients
por: Hu, Yan, et al.
Publicado: (2021)

Blockade of Autophagy Prevents the Development and Progression of Peritoneal Fibrosis
por: Shi, Yingfeng, et al.
Publicado: (2021)

Neuroprotective mechanism of TMP269, a selective class IIA histone deacetylase inhibitor, after cerebral ischemia/reperfusion injury
por: Su, Lu, et al.
Publicado: (2019)

Improved development of mouse somatic cell nuclear transfer embryos by chlamydocin analogues, class I and IIa histone deacetylase inhibitors(†)
por: Kamimura, Satoshi, et al.
Publicado: (2021)

Critical Functions of Histone Deacetylases (HDACs) in Modulating Inflammation Associated with Cardiovascular Diseases
por: Kulthinee, Supaporn, et al.
Publicado: (2022)

Prediction of histone deacetylase inhibition by triazole compounds based on artificial intelligence
por: Wang, Yiran, et al.
Publicado: (2023)

Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy
por: Sang, Yimiao, et al.
Publicado: (2018)

The effects of the histone deacetylase inhibitor 4-phenylbutyrate on gap junction conductance and permeability
por: Kaufman, Joshua, et al.
Publicado: (2013)

Histone Deacetylase SIRT1, Smooth Muscle Cell Function, and Vascular Diseases
por: Wang, Fang, et al.
Publicado: (2020)

Synergistic association of resveratrol and histone deacetylase inhibitors as treatment in amyotrophic lateral sclerosis
por: Parrella, Edoardo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_o6thnvg6ca34pscvurr01rbpig